Monocarboxylate transporters (SLC16): function, regulation, and role in health and disease
MA Felmlee, RS Jones, V Rodriguez-Cruz… - Pharmacological …, 2020 - ASPET
The solute carrier family 16 (SLC16) is comprised of 14 members of the monocarboxylate
transporter (MCT) family that play an essential role in the transport of important cell nutrients …
transporter (MCT) family that play an essential role in the transport of important cell nutrients …
The Warburg effect revisited—lesson from the Sertoli cell
PF Oliveira, AD Martins, AC Moreira… - Medicinal research …, 2015 - Wiley Online Library
Otto Warburg observed that cancerous cells prefer fermentative instead of oxidative
metabolism of glucose, although the former is in theory less efficient. Since Warburg's …
metabolism of glucose, although the former is in theory less efficient. Since Warburg's …
The molecular mechanism of sex hormones on Sertoli cell development and proliferation
Sustaining and maintaining the intricate process of spermatogenesis is liable upon
hormones and growth factors acting through endocrine and paracrine pathways. The Sertoli …
hormones and growth factors acting through endocrine and paracrine pathways. The Sertoli …
Dose-dependent effects of caffeine in human Sertoli cells metabolism and oxidative profile: relevance for male fertility
Caffeine is a widely consumed substance present in several beverages. There is an
increasing consumption of energetic drinks, rich in caffeine, among young individuals in …
increasing consumption of energetic drinks, rich in caffeine, among young individuals in …
What does androgen receptor signaling pathway in sertoli cells during normal spermatogenesis tell us?
JM Wang, ZF Li, WX Yang - Frontiers in Endocrinology, 2022 - frontiersin.org
Androgen receptor signaling pathway is necessary to complete spermatogenesis in testes.
Difference between androgen binding location in Sertoli cell classifies androgen receptor …
Difference between androgen binding location in Sertoli cell classifies androgen receptor …
Effects of elevated β-estradiol levels on the functional morphology of the testis-new insights
Elevated estradiol levels are correlated with male infertility. Causes of hyperestrogenism
include diseases of the adrenal cortex, testis or medications affecting the hypothalamus …
include diseases of the adrenal cortex, testis or medications affecting the hypothalamus …
The dark side of glucose transporters in prostate cancer: Are they a new feature to characterize carcinomas?
P Gonzalez‐Menendez, D Hevia… - … journal of cancer, 2018 - Wiley Online Library
One of the hallmarks of cancer cells is the increased ability to acquire nutrients, particularly
glucose and glutamine. Proliferating cells need precursors for cell growth and NADPH …
glucose and glutamine. Proliferating cells need precursors for cell growth and NADPH …
Antidiabetic drugs: mechanisms of action and potential outcomes on cellular metabolism
Diabetes mellitus (DM) is one of the most prevalent chronic diseases and has been a
leading cause of death in the last decades. Thus, methods to detect, prevent or delay this …
leading cause of death in the last decades. Thus, methods to detect, prevent or delay this …
Metformin and male reproduction: effects on S ertoli cell metabolism
Background and Purpose M etformin is commonly used to treat type 2 diabetes (T2D). While
new clinical applications have been ascribed to metformin, including treatment of …
new clinical applications have been ascribed to metformin, including treatment of …
The Sertoli cell as the orchestra conductor of spermatogenesis: spermatogenic cells dance to the tune of testosterone
F Dimitriadis, C Tsiampali, N Chaliasos, P Tsounapi… - Hormones, 2015 - Springer
Spermatogenesis is contingent upon hormones and growth factors acting through endocrine
and paracrine pathways either in vivo or in vitro. Sertoli cells (SCs) furnish essential factors …
and paracrine pathways either in vivo or in vitro. Sertoli cells (SCs) furnish essential factors …