Partial spontaneous intersubunit rotations in pretranslocation ribosomes

T Huang, J Choi, A Prabhakar… - Proceedings of the …, 2023 - National Acad Sciences
The two main steps of translation, peptidyl transfer, and translocation are accompanied by
counterclockwise and clockwise rotations of the large and small ribosomal subunits with …

Dynamics of ribosomes and release factors during translation termination in E. coli

S Adio, H Sharma, T Senyushkina, P Karki, C Maracci… - Elife, 2018 - elifesciences.org
Release factors RF1 and RF2 promote hydrolysis of peptidyl-tRNA during translation
termination. The GTPase RF3 promotes recycling of RF1 and RF2. Using single molecule …

Diversity and similarity of termination and ribosome rescue in bacterial, mitochondrial, and cytoplasmic translation

AA Korostelev - Biochemistry (Moscow), 2021 - Springer
When a ribosome encounters the stop codon of an mRNA, it terminates translation, releases
the newly made protein, and is recycled to initiate translation on a new mRNA. Termination …

Extensive ribosome and RF2 rearrangements during translation termination

E Svidritskiy, G Demo, AB Loveland, C Xu… - Elife, 2019 - elifesciences.org
Protein synthesis ends when a ribosome reaches an mRNA stop codon. Release factors
(RFs) decode the stop codon, hydrolyze peptidyl-tRNA to release the nascent protein, and …

Различия и сходство процессов терминации трансляции и спасения рибосомы в бактериальных клетках и в митохондриях и цитоплазме эукариотических …

АА Коростелев - Биохимия, 2021 - elibrary.ru
Когда рибосома встречает стоп-кодон на молекуле мРНК, она прекращает процесс
трансляции, высвобождает вновь синтезированный белок и разбирается на …

The design of fluorescence correlation spectroscopy for single molecule techniques

Z Norman - 2019 - mospace.umsystem.edu
The ribosome is responsible for protein synthesis--a critical process in creating essential
proteins for cell survival. Though bulk techniques yield valuable results about the structure of …