The complex functions of the liver in biosynthesis, metabolism, clearance, and host defense
are tightly dependent on an adequate microcirculation. To guarantee hepatic homeostasis …

Reactive oxygen species (ROS) are highly reactive molecules that are naturally generated
in small amounts during the body's metabolic reactions and can react with and damage …

PURPOSE: To study the nature of inflammatory reaction in eyes of patients with retinitis
pigmentosa (RP) and its possible role in the pathogenesis of RP. DESIGN: Retrospective …

Acute and chronic ethanol treatment has been shown to increase the production of reactive
oxygen species, lower cellular antioxidant levels, and enhance oxidative stress in many …

Angiotensin II (Ang II) is a pro-oxidant and fibrogenic cytokine. We investigated the role of
NADPH oxidase in Ang II–induced effects in hepatic stellate cells (HSCs), a fibrogenic cell …

Although there are numerous experimental data indicating that oxidative stress plays a role
in the initiation and progression of alcohol-induced liver disease (ALD), this work has yet to …

Reactive oxygen species (ROS) are highly reactive molecules that are naturally generated
in small amounts during the body's metabolic reactions and can react with and damage …

Molecules in biological systems often can perform more than one function. In particular,
many molecules have the ability to chemically scavenge free radicals and thus act in the test …

Significance: Hepatic fibrosis is the common pathophysiologic process resulting from
chronic liver injury, characterized by the accumulation of an excessive extracellular matrix …

Background & Aims: We explored the roles of nuclear factor-κB (NF-κB) and tumor necrosis
factor (TNF) α (TNF-α) as mediators of inflammation in a nutritional model of steatohepatitis …