Innovative immunization strategies for antivenom development
E Bermúdez-Méndez, A Fuglsang-Madsen, S Føns… - Toxins, 2018 - mdpi.com
Snakes, scorpions, and spiders are venomous animals that pose a threat to human health,
and severe envenomings from the bites or stings of these animals must be treated with …
and severe envenomings from the bites or stings of these animals must be treated with …
Biotechnological trends in spider and scorpion antivenom development
AH Laustsen, M Solà, EC Jappe, S Oscoz… - Toxins, 2016 - mdpi.com
Spiders and scorpions are notorious for their fearful dispositions and their ability to inject
venom into prey and predators, causing symptoms such as necrosis, paralysis, and …
venom into prey and predators, causing symptoms such as necrosis, paralysis, and …
Molecular, Immunological, and Biological Characterization of Tityus serrulatus Venom Hyaluronidase: New Insights into Its Role in Envenomation
CCR Horta, BF Magalhaes… - PLoS neglected …, 2014 - journals.plos.org
Background Scorpionism is a public health problem in Brazil, and Tityus serrulatus (Ts) is
primarily responsible for severe accidents. The main toxic components of Ts venom are low …
primarily responsible for severe accidents. The main toxic components of Ts venom are low …
Venom diversity in the Neotropical scorpion genus Tityus: Implications for antivenom design emerging from molecular and immunochemical analyses across endemic …
Scorpions of the Neotropical genus Tityus are responsible for most severe envenomations in
the Caribbean, South America, and Lower Central America (LCA). Although Tityus is …
the Caribbean, South America, and Lower Central America (LCA). Although Tityus is …
Recombinant Protein Containing B-Cell Epitopes of Different Loxosceles Spider Toxins Generates Neutralizing Antibodies in Immunized Rabbits
SA Lima, C Guerra-Duarte, F Costal-Oliveira… - Frontiers in …, 2018 - frontiersin.org
Loxoscelism is the most important form of araneism in South America. The treatment of these
accidents uses heterologous antivenoms obtained from immunization of production animals …
accidents uses heterologous antivenoms obtained from immunization of production animals …
[HTML][HTML] Molecular and functional characterization of metalloserrulases, new metalloproteases from the Tityus serrulatus venom gland
AO Carmo, BBR Oliveira-Mendes, CCR Horta… - Toxicon, 2014 - Elsevier
Tityus serrulatus is a Brazilian scorpion species with great medical significance. While the
effects of neurotoxins have been extensively studied, little is known about the proteases …
effects of neurotoxins have been extensively studied, little is known about the proteases …
Amazonian scorpions and scorpionism: integrating toxinological, clinical, and phylogenetic data to combat a human health crisis in the world's most diverse rainforest
Venom from Amazonian scorpions of the genus Tityus contains components capable of
eliciting a distinct clinical, mostly neurological, syndrome. This contrasts with the mainly …
eliciting a distinct clinical, mostly neurological, syndrome. This contrasts with the mainly …
Evolution of alternative methodologies of scorpion antivenoms production
AO Carmo, M Chatzaki, CCR Horta, BF Magalhães… - Toxicon, 2015 - Elsevier
Scorpionism represents a serious public health problem resulting in the death of children
and debilitated individuals. Scorpion sting treatment employs various strategies including …
and debilitated individuals. Scorpion sting treatment employs various strategies including …
Protection against the toxic effects of Loxosceles intermedia spider venom elicited by mimotope peptides
J De Moura, L Felicori, V Moreau, G Guimarães… - Vaccine, 2011 - Elsevier
The venom of Loxosceles intermedia (Li) spiders is responsible for cutaneous lesions and
other clinical manifestations. We previously reported that the monoclonal antibody LimAb7 …
other clinical manifestations. We previously reported that the monoclonal antibody LimAb7 …
Determination of the Rituximab Binding Site to the CD20 Epitope Using SPOT Synthesis and Surface Plasmon Resonance Analyses
L Bar, C Nguyen, M Galibert… - Analytical …, 2021 - ACS Publications
Antibodies not only play a major role in clinical diagnostics and biopharmaceutical analysis
but also are a class of drugs that are regularly used to treat numerous diseases. The …
but also are a class of drugs that are regularly used to treat numerous diseases. The …