The P-element has been the workhorse of Drosophila genetics since it was developed as a
tool for transgenesis in 1982; the subsequent development of a variety of systems based on …

Transposable elements (TEs) are both important drivers of genome evolution and genetic
parasites with potentially dramatic consequences for host fitness. The recent explosion of …

Genetic studies of the mariner transposable element Mos1 have revealed two novel types of
regulatory mechanisms. In one mechanism, overproduction of the wild-type transposase …

Transposable elements of the mariner family are widespread among insects and other
invertebrates, and initial analyses of their relationships indicated frequent occurrence of …

Transposable elements are short but complex pieces of DNA or RNA containing a
streamlined minimal-genome with the capacity for its selfish replication in a foreign genomic …

Binding of a multiprotein complex to a 5'exon inhibitory element appears to repress splicing
of the Drosophila P-element third intron (IVS3) in the soma. We have purified 97-and 50-kD …

In Drosophila melanogaster, hybrid dysgenesis occurs in progeny from crosses between
females lacking P elements and males carrying P elements scattered throughout the …

P transposable elements are one of the best‐studied eukaryotic mobile DNA elements in
metazoans. These elements were initially discovered in the late 1960's because they cause …

PSI is an RNA-binding protein involved in repressing splicing of the P element third intron in
Drosophila somatic cell extracts. PSI produced in bacteria restores splicing inhibition to an …

▪ Abstract Transposable elements propagate by inserting into new locations in the genomes
of the hosts they inhabit. Their transposition might thus negatively affect the fitness of the …