Current state of the art for enhancing urine biomarker discovery
M Harpole, J Davis, V Espina - Expert review of Proteomics, 2016 - Taylor & Francis
Introduction: Urine is a highly desirable biospecimen for biomarker analysis because it can
be collected recurrently by non-invasive techniques, in relatively large volumes. Urine …
be collected recurrently by non-invasive techniques, in relatively large volumes. Urine …
Biomarker discovery in mass spectrometry‐based urinary proteomics
Urinary proteomics has become one of the most attractive topics in disease biomarker
discovery. MS‐based proteomic analysis has advanced continuously and emerged as a …
discovery. MS‐based proteomic analysis has advanced continuously and emerged as a …
Proteomic characterization of hempseed (Cannabis sativa L.)
G Aiello, E Fasoli, G Boschin, C Lammi, C Zanoni… - Journal of …, 2016 - Elsevier
This paper presents an investigation on hempseed proteome. The experimental approach,
based on combinatorial peptide ligand libraries (CPLLs), SDS-PAGE separation, nLC-ESI …
based on combinatorial peptide ligand libraries (CPLLs), SDS-PAGE separation, nLC-ESI …
Assessment of the floral origin of honey via proteomic tools
F Di Girolamo, A D'Amato, PG Righetti - Journal of proteomics, 2012 - Elsevier
The honey from chestnut, acacia, sunflower, eucalyptus and orange was analysed for its
proteome content, in order to see if any plant proteins present would allow the proteo-typing …
proteome content, in order to see if any plant proteins present would allow the proteo-typing …
[HTML][HTML] In-depth exploration of cerebrospinal fluid by combining peptide ligand library treatment and label-free protein quantification
E Mouton-Barbosa, F Roux-Dalvai, D Bouyssié… - Molecular & Cellular …, 2010 - ASBMB
Cerebrospinal fluid (CSF) is the biological fluid in closest contact with the brain and thus
contains proteins of neural cell origin. Hence, CSF is a biochemical window into the brain …
contains proteins of neural cell origin. Hence, CSF is a biochemical window into the brain …
With or without you—Proteomics with or without major plasma/serum proteins
E Gianazza, I Miller, L Palazzolo, C Parravicini… - Journal of …, 2016 - Elsevier
The first sections of this review compile and discuss strategies and protocols for managing
plasma/serum as a source of biomarkers relevant to human disease. In many such cases …
plasma/serum as a source of biomarkers relevant to human disease. In many such cases …
Resolubilization of precipitated intact membrane proteins with cold formic acid for analysis by mass spectrometry
AA Doucette, DB Vieira, DJ Orton… - Journal of Proteome …, 2014 - ACS Publications
Protein precipitation in organic solvent is an effective strategy to deplete sodium dodecyl
sulfate (SDS) ahead of MS analysis. Here we evaluate the recovery of membrane and water …
sulfate (SDS) ahead of MS analysis. Here we evaluate the recovery of membrane and water …
Advances in purification and separation of posttranslationally modified proteins
Posttranslational modifications (PTMs) of proteins represent fascinating extensions of the
dynamic complexity of living cells' proteomes. The results of enzymatically catalyzed or …
dynamic complexity of living cells' proteomes. The results of enzymatically catalyzed or …
[HTML][HTML] An experimental workflow for enrichment of low abundant proteins from human serum for the discovery of serum biomarkers
Serum contains proteins that possess important information about diseases and their
progression. Unfortunately, these proteins, which carry the information in the serum are in …
progression. Unfortunately, these proteins, which carry the information in the serum are in …
From hundreds to thousands: Widening the normal human Urinome (1)
L Santucci, G Candiano, A Petretto, M Bruschi… - Journal of …, 2015 - Elsevier
It is currently unknown how many proteins can be detected in urine. Improving the analytical
approach would increase their number and potentially strengthen their predictive potential in …
approach would increase their number and potentially strengthen their predictive potential in …