Lipid nanoparticles─ from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement
R Tenchov, R Bird, AE Curtze, Q Zhou - ACS nano, 2021 - ACS Publications
Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …
Recent progress in nanostructured smart drug delivery systems for cancer therapy: a review
Traditional treatment approaches for cancer involve intravenous chemotherapy or other
forms of drug delivery. These therapeutic measures suffer from several limitations such as …
forms of drug delivery. These therapeutic measures suffer from several limitations such as …
Breast cancer: Biology, biomarkers, and treatments
During the past recent years, various therapies emerged in the era of breast cancer. Breast
cancer is a heterogeneous disease in which genetic and environmental factors are involved …
cancer is a heterogeneous disease in which genetic and environmental factors are involved …
Smart nanomaterials in cancer theranostics: challenges and opportunities
Cancer is ranked as the second leading cause of death globally. Traditional cancer
therapies including chemotherapy are flawed, with off-target and on-target toxicities on the …
therapies including chemotherapy are flawed, with off-target and on-target toxicities on the …
Novel nanomedicines to overcome cancer multidrug resistance
Chemotherapy remains a powerful tool to eliminate malignant cells. However, the efficacy of
chemotherapy is compromised by the frequent emergence of intrinsic and acquired …
chemotherapy is compromised by the frequent emergence of intrinsic and acquired …
The mRNA vaccine revolution: COVID-19 has launched the future of vaccinology
During the COVID-19 pandemic, mRNA (mRNA) vaccines emerged as leading vaccine
candidates in a record time. Nonreplicating mRNA (NRM) and self-amplifying mRNA (SAM) …
candidates in a record time. Nonreplicating mRNA (NRM) and self-amplifying mRNA (SAM) …
Specific targeting cancer cells with nanoparticles and drug delivery in cancer therapy
S Raj, S Khurana, R Choudhari, KK Kesari… - Seminars in cancer …, 2021 - Elsevier
Nanotechnology has been the latest approach for diagnosis and treatment for cancer, which
opens up a new alternative therapeutic drug delivery option to treat disease. Nanoparticles …
opens up a new alternative therapeutic drug delivery option to treat disease. Nanoparticles …
Nanoparticles in clinical trials: analysis of clinical trials, FDA approvals and use for COVID-19 vaccines
Nanoparticles are heterologous small composites that are usually between 1 and 100
nanometers in size. They are applied in many areas of medicine with one of them being …
nanometers in size. They are applied in many areas of medicine with one of them being …
[HTML][HTML] Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells
While the distant organ environment is known to support metastasis of primary tumors, its
metabolic roles in this process remain underdetermined. Here, in breast cancer models, we …
metabolic roles in this process remain underdetermined. Here, in breast cancer models, we …
[HTML][HTML] Nano-based drug delivery systems: Conventional drug delivery routes, recent developments and future prospects
Drug delivery can be defined as the group of approaches a drug or pharmacologically active
agent can be transported to the target cell to treat disease or health issue. Conventional …
agent can be transported to the target cell to treat disease or health issue. Conventional …