Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that affects multiple
organ systems and is caused by loss-of-function mutations in one of two genes: TSC1 or …

Autism spectrum disorder (ASD) represents a heterogeneous group of disorders, which
presents a substantial challenge to diagnosis and treatment. Over the past decade …

Autism is a severe neurobehavioral syndrome, arising largely as an inherited disorder,
which can arise from several diseases. Despite recent advances in identifying some genes …

Background Tuberous sclerosis complex is a multisystem genetic disorder with a range of
physical manifestations that require evaluation, surveillance, and management. Individuals …

Malignant migrating partial seizures of infancy (MMPSI) is a rare epileptic encephalopathy of
infancy that combines pharmacoresistant seizures with developmental delay. We performed …

Co-occurring medical disorders and associated physiological abnormalities in individuals
with autism spectrum disorder (ASD) may provide insight into causal pathways or underlying …

Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders that is among the
most severe in terms of prevalence, morbidity and impact to the society. It is characterized by …

Autism is more common in people with epilepsy, approximately 20%, and epilepsy is more
common in people with autism with reported rates of approximately 20%. However, these …

39 interacting with others and may even approach people for attention more often than
children without ADHD. In addition, the intensity the children with ADHD show in their …

Twin and family studies in autistic disorders (AD) have elucidated a high heritability of the
narrow and broad phenotype of AD. In this review on the genetics of AD, we will initially …