[HTML][HTML] Pulmonary innate immune response determines the outcome of inflammation during pneumonia and sepsis-associated acute lung injury

V Kumar - Frontiers in immunology, 2020 - frontiersin.org
The lung is a primary organ for gas exchange in mammals that represents the largest
epithelial surface in direct contact with the external environment. It also serves as a crucial …

Integrative physiology of pneumonia

LJ Quinton, AJ Walkey, JP Mizgerd - Physiological reviews, 2018 - journals.physiology.org
Pneumonia is a type of acute lower respiratory infection that is common and severe. The
outcome of lower respiratory infection is determined by the degrees to which immunity is …

[HTML][HTML] Natural killer cells in the lungs

J Cong, H Wei - Frontiers in immunology, 2019 - frontiersin.org
The lungs, a special site that is frequently challenged by tumors, pathogens and other
environmental insults, are populated by large numbers of innate immune cells. Among …

[HTML][HTML] Natural cytotoxicity receptors: broader expression patterns and functions in innate and adaptive immune cells

K Hudspeth, B Silva-Santos, D Mavilio - Frontiers in immunology, 2013 - frontiersin.org
Natural cytotoxicity receptors (NCRs) have been classically defined as activating receptors
delivering potent signals to Natural Killer (NK) cells in order to lyze harmful cells and to …

[HTML][HTML] Consequences of the crosstalk between monocytes/macrophages and natural killer cells

T Michel, F Hentges, J Zimmer - Frontiers in immunology, 2013 - frontiersin.org
The interaction between natural killer (NK) cells and different other immune cells like T cells
and dendritic cells is well-described, but the crosstalk with monocytes or macrophages and …

Viral–bacterial interactions in the respiratory tract

C Bellinghausen, GGU Rohde… - Journal of General …, 2016 - microbiologyresearch.org
In the respiratory tract, viruses and bacteria can interact on multiple levels. It is well known
that respiratory viruses, particularly influenza viruses, increase the susceptibility to …

[HTML][HTML] Tissue-resident immunity in the lung: a first-line defense at the environmental interface

DE Zazara, I Belios, J Lücke, T Zhang… - Seminars in …, 2022 - Springer
The lung is a vital organ that incessantly faces external environmental challenges. Its
homeostasis and unimpeded vital function are ensured by the respiratory epithelium …

[HTML][HTML] Low circulating natural killer cell counts are associated with severe disease in patients with common variable immunodeficiency

M Ebbo, L Gérard, S Carpentier, F Vély, S Cypowyj… - …, 2016 - thelancet.com
Natural Killer (NK) cells have been shown to exert antiviral and antitumoural activities.
Nevertheless most available data are derived from mouse models and functions of these …

[HTML][HTML] NKp46 clusters at the immune synapse and regulates NK cell polarization

U Hadad, TJ Thauland, OM Martinez, MJ Butte… - Frontiers in …, 2015 - frontiersin.org
Natural killer (NK) cells play an important role in first-line defense against tumor and virus-
infected cells. The activity of NK cells is tightly regulated by a repertoire of cell surface …

Bright fluorescent Streptococcus pneumoniae for live-cell imaging of host-pathogen interactions

M Kjos, R Aprianto, VE Fernandes… - Journal of …, 2015 - Am Soc Microbiol
Streptococcus pneumoniae is a common nasopharyngeal resident in healthy people but, at
the same time, one of the major causes of infectious diseases such as pneumonia …