Advantages and challenges of the spray-drying technology for the production of pure drug particles and drug-loaded polymeric carriers

A Sosnik, KP Seremeta - Advances in colloid and interface science, 2015 - Elsevier
Spray-drying is a rapid, continuous, cost-effective, reproducible and scalable process for the
production of dry powders from a fluid material by atomization through an atomizer into a hot …

Green biopolymers from by-products as wall materials for spray drying microencapsulation of phytochemicals

K Samborska, S Boostani, M Geranpour… - Trends in Food Science …, 2021 - Elsevier
Background Spray drying is still the most important technique for the microencapsulation of
bioactive ingredients. It makes possible to create easy-handling powdered microcapsules …

Nanomedicine formulations for the delivery of antiviral drugs: a promising solution for the treatment of viral infections

D Lembo, M Donalisio, A Civra… - Expert Opinion on …, 2018 - Taylor & Francis
Introduction: Viral infections represent a public health problem and one of the leading
causes of global mortality. Nanomedicine strategies can be considered a powerful tool to …

Optimization to development of chitosan decorated polycaprolactone nanoparticles for improved ocular delivery of dorzolamide: In vitro, ex vivo and toxicity …

MS Shahab, M Rizwanullah, S Alshehri… - International journal of …, 2020 - Elsevier
The present research work was designed to develop dorzolamide-loaded chitosan-coated
polycaprolactone nanoparticles (DRZ-CS-PCL-NPs) for improved ocular delivery. The …

Hybrid bioactive hydroxyapatite/polycaprolactone nanoparticles for enhanced osteogenesis

SE El-Habashy, HM Eltaher, A Gaballah, EI Zaki… - Materials Science and …, 2021 - Elsevier
Hydroxyapatite nanoparticles (HApN) are largely employed as osteogenic inorganic
material. Inorganic/polymeric hybrid nanostructures can provide versatile bioactivity for …

Challenges in oral drug delivery of antiretrovirals and the innovative strategies to overcome them

A Sosnik, R Augustine - Advanced drug delivery reviews, 2016 - Elsevier
Abstract Development of novel drug delivery systems (DDS) represents a promising
opportunity to overcome the various bottlenecks associated with the chronic antiretroviral …

Spray drying as an advantageous strategy for enhancing pharmaceuticals bioavailability

AH Salama - Drug Delivery and Translational Research, 2020 - Springer
Spray drying is an efficient technique that is used not only for rapid evaporation of the
solvent from different systems but also for designing ultra-fine particles with various …

Enhancement of solubility, antioxidant ability and bioavailability of taxifolin nanoparticles by liquid antisolvent precipitation technique

Y Zu, W Wu, X Zhao, Y Li, W Wang, C Zhong… - International journal of …, 2014 - Elsevier
Taxifolin is a kind of flavanonol, whose antioxidant ability is superior to that of ordinary
flavonoids compounds owing to its special structure. However, its low bioavailability is a …

Electrohydrodynamic atomization and spray-drying for the production of pure drug nanocrystals and co-crystals

RS Arzi, A Sosnik - Advanced drug delivery reviews, 2018 - Elsevier
In recent years, nanotechnology has offered attractive opportunities to overcome the (bio)
pharmaceutical drawbacks of most drugs such as low aqueous solubility and bioavailability …

Enhancement of oral bioavailability of anti-HIV drug rilpivirine HCl through nanosponge formulation

R Zainuddin, Z Zaheer, JN Sangshetti… - Drug development and …, 2017 - Taylor & Francis
Objective: To synthesize β cyclodextrin nanosponges using a novel and efficient microwave
mediated method for enhancing bioavailability of Rilpivirine HCl (RLP). Significance …