After the publication of the revised edition, therapeutic drugs described in “Future Treatment”
were approved and important evidence for pharmacologic therapy and nonpharmacologic …

The considerable mortality and morbidity associated with atrial fibrillation (AF) pose a
substantial burden on patients and health care services. Although the management of AF …

Intervention at the earliest illness stage, in ultra or clinical high-risk individuals, or indicated
prevention, currently represents the most promising strategy to ameliorate, delay or prevent …

Ischemic strokes related to atrial fibrillation are highly prevalent, presenting with severe
neurologic syndromes and associated with high risk of recurrence. Although advances have …

Background Residual risk of ischemic stroke despite anticoagulation in patients with atrial
fibrillation (AF) represents a significant clinical issue that remains unaddressed. We aimed to …

In contrast to current guidelines and earlier trials, recent studies demonstrated superiority of
rhythm-over rate-control and challenged the strategy of" rate versus rhythm" therapy in …

Aims Atrial fibrillation (AF) recurrence during the first year after catheter ablation remains
common. Patient-specific prediction of arrhythmic recurrence would improve patient …

Background: Catheter ablation has become a well-established indication for long-term
rhythm control in atrial fibrillation (AF) patients refractory to anti-arrhythmic drugs (AADs) …

AF contributes to increased stroke risk via various mechanisms, including deranged blood
constituents, vessel wall abnormalities and abnormal blood flow. This excess risk is …

Introduction Catheter ablation for atrial fibrillation (AF) in comparison to medical therapy
alone is known to improve freedom from arrhythmia and quality of life, but the benefit …