The threat of novel influenza infections has sparked research efforts to develop subunit
vaccines that can induce a more broadly protective immunity by targeting selected regions of …

Introduction: Current influenza vaccines are mainly produced from viruses propagated in
eggs, an established process developed over 70 years. However, this technology presents …

Laboratory mice comprise an expeditious model for preclinical vaccine testing; however,
vaccine immunogenicity in these models often inadequately translates to humans …

Influenza vaccines have been available for over 80 years. They have contributed to
significant reductions in influenza morbidity and mortality. However, there have been …

Secondary infections arise as a consequence of previous or concurrent conditions and
occur in the community or in the hospital setting. The events allowing secondary infections to …

The vast majority of people already have preexisting immune responses to influenza viruses
from one or more subtypes. However, almost all preclinical studies evaluate new influenza …

Current influenza vaccines offer suboptimal protection and depend on annual reformulation
and yearly administration. Vaccine technology has rapidly advanced during the last decade …

OBJECTIVES: To systematically review the literature on early childhood health associated
with exposure to influenza vaccines in utero. DATA SOURCES: We searched CINAHL Plus …

Current seasonal influenza vaccines have suboptimal effectiveness, especially in seasons
dominated by viruses that do not match the vaccine. Therefore, finding new approaches to …

Background There is substantial burden of seasonal influenza in Kenya, which led the
government to consider introducing a national influenza vaccination programme. Given the …