Molecular docking and experimental investigation of new indole derivative cyclooxygenase inhibitor to probe its binding mechanism with bovine serum albumin
Abstract The indole derivative 2-(5-methoxy-2-methyl-1H-indol-3-yl)-N'-[(E)-(3-nitrophenyl)
methylidene] acetohydrazide (IND) was synthesized for its therapeutic potential to inhibit …
methylidene] acetohydrazide (IND) was synthesized for its therapeutic potential to inhibit …
Inhibitory effects of usnic and carnosic acid on some metabolic enzymes: an in vitro study
Background: Natural products are produced via primary and secondary metabolism in
different organisms. The compounds obtained via secondary metabolism are not essential …
different organisms. The compounds obtained via secondary metabolism are not essential …
Zinc nitride quantum dots as an efficient probe for simultaneous fluorescence detection of Cu2+ and Mn2+ ions in water samples
The exceptional ascending heights of graphene (carbon) and boron nitride nanostructures
have invited scientists to explore metal nitride nanomaterials. Herein, Zn3N2 quantum dots …
have invited scientists to explore metal nitride nanomaterials. Herein, Zn3N2 quantum dots …
New insights into the binding mechanism between osthole and β-lactoglobulin: Spectroscopic, chemometrics and docking studies
R Wang, Y Liu, X Hu, J Pan, D Gong… - Food Research …, 2019 - Elsevier
Osthole, a type of coumarin derivative, owns many biological functions, but the poor water
solubility and low bioavailability limit its usage in food and pharmaceutical fields. β …
solubility and low bioavailability limit its usage in food and pharmaceutical fields. β …
Interaction of promethazine and adiphenine to human hemoglobin: A comparative spectroscopic and computational analysis
The binding nature of amphiphilic drugs viz. promethazine hydrochloride (PMT) and
adiphenine hydrochloride (ADP), with human hemoglobin (Hb) was unraveled by …
adiphenine hydrochloride (ADP), with human hemoglobin (Hb) was unraveled by …
Interaction of norfloxacin with bovine serum albumin studied by different spectrometric methods; displacement studies, molecular modeling and chemometrics …
A Naseri, S Hosseini, F Rasoulzadeh, MR Rashidi… - Journal of …, 2015 - Elsevier
Serum albumins as major target proteins can bind to other ligands leading to alteration of
their pharmacological properties. The mechanism of interaction between norfloxacin (NFLX) …
their pharmacological properties. The mechanism of interaction between norfloxacin (NFLX) …
Potent drug candidature of an ONS donor tethered copper (II) complex: Anticancer activity, cytotoxicity and spectroscopically approached BSA binding studies
In our continued efforts to develop metal based therapeutic agents, we have synthesized a
novel copper (II) complex,[{Cu (hpdbal-sbdt)} 2](2) tethered with a biocompatible ONS 2 …
novel copper (II) complex,[{Cu (hpdbal-sbdt)} 2](2) tethered with a biocompatible ONS 2 …
An aqueous solution of fluorescent MoS2 quantum dots toward a sensitive and selective probe for Fe3+: A tri-mode spectroscopic sensing technique
In this work, MoS 2 quantum dots (MSQDs) of average size∼ 3.0±1.2 nm in aqueous
medium were synthesized by simple technique. Three different emissive sites of MSQDs …
medium were synthesized by simple technique. Three different emissive sites of MSQDs …
A spectroscopic and molecular dynamic approach on the interaction between ionic liquid type gemini surfactant and human serum albumin
JK Maurya, MUH Mir, N Maurya, N Dohare… - Journal of …, 2016 - Taylor & Francis
The interactions of imidazolium bashed ionic liquid-type cationic gemini surfactant ([C12-4-
C12im] Br2) with HSA were studied by fluorescence, time-resolved fluorescence, UV-visible …
C12im] Br2) with HSA were studied by fluorescence, time-resolved fluorescence, UV-visible …
Molecular interaction of functionalized nanoplastics with human hemoglobin
D Rajendran, N Chandrasekaran - Journal of Fluorescence, 2023 - Springer
Humans are exposed to excessive nanoplastics (NPs) which have ample affinity for globular
proteins. We investigated the interaction of functionalized polystyrene nanoplastics (plain …
proteins. We investigated the interaction of functionalized polystyrene nanoplastics (plain …