The natural history of nonalcoholic fatty liver disease—an evolving view

CC Lindenmeyer, AJ McCullough - Clinics in liver disease, 2018 - liver.theclinics.com
Since first described in 1980, 1 nonalcoholic fatty liver disease (NAFLD) is defined as the
accumulation of hepatic fat, as evidenced by radiologic or histologic examination, in the …

AISF position paper on nonalcoholic fatty liver disease (NAFLD): Updates and future directions

A Lonardo, F Nascimbeni, G Targher… - Digestive and Liver …, 2017 - Elsevier
This review summarizes our current understanding of nonalcoholic fatty liver disease
(NAFLD), a multi-factorial systemic disease resulting from a complex interaction between a …

Empagliflozin improves liver steatosis and fibrosis in patients with non-alcoholic fatty liver disease and type 2 diabetes: a randomized, double-blind, placebo …

H Chehrehgosha, MR Sohrabi, F Ismail-Beigi… - Diabetes Therapy, 2021 - Springer
Introduction To evaluate the efficacy of empagliflozin compared to pioglitazone in patients
with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2DM). Methods In this …

Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review

R Harris, DJ Harman, TR Card, GP Aithal… - The lancet …, 2017 - thelancet.com
As of 2016, there is no evidence-based pathway to stratify the risk of chronic liver disease in
a general population setting. Non-invasive tests of liver fibrosis might provide a mechanism …

Liver fibrosis by FibroScan® independently of established cardiovascular risk parameters associates with macrovascular and microvascular complications in patients …

R Lombardi, L Airaghi, G Targher, G Serviddio… - Liver …, 2020 - Wiley Online Library
Abstract Background & Aims Non‐alcoholic fatty liver disease (NAFLD) and type 2 diabetes
mellitus (T2DM) are closely associated, and liver fibrosis has been related to macrovascular …

[HTML][HTML] Diagnostic performance of FibroTouch ultrasound attenuation parameter and liver stiffness measurement in assessing hepatic steatosis and fibrosis in …

Y Qu, YY Song, CW Chen, QC Fu, JP Shi… - Clinical and …, 2021 - journals.lww.com
METHODS: We recruited 237 patients undergoing FibroTouch and liver biopsy within 2
weeks. The pathological findings of liver biopsy were scored by Nonalcoholic …

Range of normal liver stiffness and factors associated with increased stiffness measurements in apparently healthy individuals

F Bazerbachi, S Haffar, Z Wang, J Cabezas… - Clinical …, 2019 - Elsevier
Background & Aims Transient elastography (TE) is a noninvasive technique used to
measure liver stiffness to estimate the severity of fibrosis. The range of liver stiffness …

[HTML][HTML] Accuracy of transient elastography-FibroScan®, acoustic radiation force impulse (ARFI) imaging, the enhanced liver fibrosis (ELF) test, APRI, and the FIB-4 …

TG Ragazzo, D Paranagua-Vezozzo, FR Lima… - Clinics, 2017 - SciELO Brasil
OBJECTIVES: Although liver biopsy is the gold standard for determining the degree of liver
fibrosis, issues regarding its invasiveness and the small amount of liver tissue evaluated can …

New insights into non-alcoholic fatty liver disease and coronary artery disease: The liver-heart axis

GD Cazac, CM Lăcătușu, C Mihai, ED Grigorescu… - Life, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) represents the hepatic expression of the metabolic
syndrome and is the most prevalent liver disease. NAFLD is associated with liver-related …

Screening for liver fibrosis in the general population: where do we stand in 2022?

CM Canivet, J Boursier - Diagnostics, 2022 - mdpi.com
Approximately 30% of the worldwide population has at least one risk factor for liver disease.
Identifying advanced liver disease before the occurrence of complications remains a difficult …