Because of their potent antitumor activity and their proinflammatory role, natural killer (NK)
cells are at the forefront of efforts to develop immuno-oncologic treatments. NK cells …

Natural killer (NK) cells are innate immune cells that show strong cytolytic function against
physiologically stressed cells such as tumor cells and virus-infected cells. NK cells show a …

Natural killer (NK) cells are commonly reduced in human tumors, enabling many to evade
surveillance. Here, we sought to identify cues that alter NK cell activity in tumors. We found …

Immune associated cells in the microenvironment have a significant impact on the
development and progression of hepatocellular carcinoma (HCC) and have received more …

Colorectal cancer (CRC), as a prominent cause of cancer-related deaths, has historically
been notable worldwide and many attempts have been made to raise the overall survival of …

The immune landscape of a tumor is highly connected to patient prognosis and response to
treatment, but little is known about how natural killer (NK) cells predict overall survival (OS) …

Immune escape is a hallmark of cancer. The dynamic and heterogeneous tumour
microenvironment (TME) causes insufficient infiltration and poor efficacy of natural killer (NK) …

Objective Tumour-infiltrating lymphocytes (TILs) favour survival in human colorectal cancer
(CRC). Chemotactic factors underlying their recruitment remain undefined. We investigated …

In addition to the contribution of cancer cells, the solid tumor microenvironment (TME) has a
critical role in determining tumor expansion, antitumor immunity, and the response to …

Carcinomas are complex heterocellular systems containing epithelial cancer cells, stromal
fibroblasts, and multiple immune cell‐types. Cell‐cell communication between these tumor …