The apolipoprotein E locus (APOE) is associated with variations in the age of onset and risk
of Alzheimer's disease. The APOE4 allele increases the probability of disease at an earlier …

Inheritance of specific apolipoprotein E (apoE) alleles determines, in large part, the risk and
mean age of onset of late-onset familial and sporadic Alzheimer disease. The mechanism by …

Background: The APOE gene and its protein product is associated with a number of plasma
proteins like very-low density lipoprotein (VLDL), high density lipoprotein (HDL) …

The strength of the evidence implicating aluminium as an important factor in the dementia of
Alzheimer's disease (AD) is reviewed. We submit that the weight of the epidemiological and …

The genetics of Alzheimer disease (AD) are complex and not completely understood.
Mutations in the amyloid precursor protein gene (APP) can cause early-onset autosomal …

Background: Published studies now show a clear association between Alzheimer's disease
(AD) and the apolipoprotein E ε4 allele (APOE* ε4). The clinical value of this information to …

In order to quantify the effects of apolipoprotein (apo) E on early-and late-onset, sporadic
and familial Alzheimer's disease (AD) more precisely we performed a meta-analysis of 42 …

The distribution of apolipoprotein E (APOE) genotypes as a function of age and sex has
been examined in a French population of 417 Alzheimer disease (AD) patients and 1,030 …

Article abstract-Given the relationship between the presence of ApoE epsilon 4 and
Alzheimer's disease (AD), we studied whether knowledge of epsilon 4 status would predict …

Objective: To test whether cholesterol ester transfer protein (CETP) genotype (VV
homozygosity for I405V) is associated with preservation of cognitive function in addition to its …