Apolipoprotein E and Alzheimer's disease
WJ Strittmatter, AD Roses - Annual review of neuroscience, 1996 - annualreviews.org
The apolipoprotein E locus (APOE) is associated with variations in the age of onset and risk
of Alzheimer's disease. The APOE4 allele increases the probability of disease at an earlier …
of Alzheimer's disease. The APOE4 allele increases the probability of disease at an earlier …
Apolipoprotein E and Alzheimer disease.
WJ Strittmatter, AD Roses - Proceedings of the National …, 1995 - National Acad Sciences
Inheritance of specific apolipoprotein E (apoE) alleles determines, in large part, the risk and
mean age of onset of late-onset familial and sporadic Alzheimer disease. The mechanism by …
mean age of onset of late-onset familial and sporadic Alzheimer disease. The mechanism by …
APOE distribution in world populations with new data from India and the UK
PP Singh, M Singh, SS Mastana - Annals of human biology, 2006 - Taylor & Francis
Background: The APOE gene and its protein product is associated with a number of plasma
proteins like very-low density lipoprotein (VLDL), high density lipoprotein (HDL) …
proteins like very-low density lipoprotein (VLDL), high density lipoprotein (HDL) …
Aluminium and the risk for Alzheimer's disease
DRC McLachlan - Environmetrics, 1995 - Wiley Online Library
The strength of the evidence implicating aluminium as an important factor in the dementia of
Alzheimer's disease (AD) is reviewed. We submit that the weight of the epidemiological and …
Alzheimer's disease (AD) is reviewed. We submit that the weight of the epidemiological and …
Genetic dissection of Alzheimer disease, a heterogeneous disorder.
GD Schellenberg - Proceedings of the National Academy of …, 1995 - National Acad Sciences
The genetics of Alzheimer disease (AD) are complex and not completely understood.
Mutations in the amyloid precursor protein gene (APP) can cause early-onset autosomal …
Mutations in the amyloid precursor protein gene (APP) can cause early-onset autosomal …
Apolipoprotein E ε4 allele and the lifetime risk of Alzheimer's disease: What physicians know, and what they should know
S Seshadri, DA Drachman, CF Lippa - Archives of neurology, 1995 - jamanetwork.com
Background: Published studies now show a clear association between Alzheimer's disease
(AD) and the apolipoprotein E ε4 allele (APOE* ε4). The clinical value of this information to …
(AD) and the apolipoprotein E ε4 allele (APOE* ε4). The clinical value of this information to …
Apolipoprotein E genetic variation and Alzheimer's disease: a meta-analysis
DC Rubinsztein, DF Easton - Dementia and geriatric cognitive disorders, 1999 - karger.com
In order to quantify the effects of apolipoprotein (apo) E on early-and late-onset, sporadic
and familial Alzheimer's disease (AD) more precisely we performed a meta-analysis of 42 …
and familial Alzheimer's disease (AD) more precisely we performed a meta-analysis of 42 …
Apolipoprotein E and Alzheimer disease: genotype-specific risks by age and sex.
H Bickeböller, D Campion, A Brice… - American journal of …, 1997 - ncbi.nlm.nih.gov
The distribution of apolipoprotein E (APOE) genotypes as a function of age and sex has
been examined in a French population of 417 Alzheimer disease (AD) patients and 1,030 …
been examined in a French population of 417 Alzheimer disease (AD) patients and 1,030 …
A prospective study of the clinical utility of ApoE genotype in the prediction of outcome in patients with memory impairment
MC Tierney, JP Szalai, WG Snow, RH Fisher, T Tsuda… - Neurology, 1996 - AAN Enterprises
Article abstract-Given the relationship between the presence of ApoE epsilon 4 and
Alzheimer's disease (AD), we studied whether knowledge of epsilon 4 status would predict …
Alzheimer's disease (AD), we studied whether knowledge of epsilon 4 status would predict …
A genotype of exceptional longevity is associated with preservation of cognitive function
N Barzilai, G Atzmon, CA Derby, JM Bauman… - Neurology, 2006 - AAN Enterprises
Objective: To test whether cholesterol ester transfer protein (CETP) genotype (VV
homozygosity for I405V) is associated with preservation of cognitive function in addition to its …
homozygosity for I405V) is associated with preservation of cognitive function in addition to its …