The peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a well-known
transcriptional coactivator involved in mitochondrial biogenesis. PGC-1α is implicated in the …

Social recognition is the sensitive domains of complex behavior critical for identification,
interpretation and storage of socially meaningful information. Social recognition develops …

Ischemic stroke is one of the major causes of morbidity and mortality worldwide.
Mitochondria play a vital role in the pathological processes of cerebral ischemic injury, but …

Alzheimer's disease (AD) is a devastating, progressive neurodegenerative disorder that
leads to severe cognitive impairment in elderly patients. Chronic neuroinflammation plays …

Inflammatory mediators released from activated microglia, astrocytes, neurons, and mast
cells mediate neuroinflammation. Parkinson's disease (PD) is characterized by inflammation …

Neuroinflammation plays an active role in the pathogenesis of several neurodegenerative
diseases, including Parkinson's disease (PD). Earlier studies from this laboratory showed …

Corticotropin-releasing hormone is a critical component of the hypothalamic–pituitary–
adrenal axis, which plays a major role in the body's immune response to stress. Mast cells …

Alzheimer's disease (AD) is an incurable, progressive and devastating neurodegenerative
disease. Pathogenesis of AD is associated with the aggregation and accumulation of …

Despite significant advancements in the field of molecular neurobiology especially
neuroinflammation and neurodegeneration, the highly complex molecular mechanisms …

Optic neuritis (ON), characterized by inflammation of the optic nerve and apoptosis of retinal
ganglion cells (RGCs), is one of the leading causes of blindness in patients. Given that RGC …