Animal models of epilepsy and seizures, mostly involving mice and rats, are used to
understand the pathophysiology of the different forms of epilepsy and their comorbidities, to …

Rats and mice are widely used to study environmental effects on psychological and
metabolic health. Study designs differ widely and are often characterized by varying (social) …

In rats reared without play, or with limited access to play during the juvenile period, the
dendrites of pyramidal neurons of the medial prefrontal cortex (mPFC) exhibit more …

In 1963, the National Institutes of Health (NIH) first issued guidelines for animal housing and
husbandry. The most recent 2010 revision emphasizes animal care “in ways judged to be …

Alcohol use disorder (AUD) and anxiety disorders are frequently comorbid and share
mechanisms that could be therapeutic targets. To facilitate mechanistic studies, we adapted …

Cannabis and alcohol co-use is prevalent in adolescence, but the long-term behavioural
effects of this co-use remain largely unexplored. The aim of this study is to investigate the …

Stress or low level of estrogen could promote anxiety and depression; thus, it is of interest to
investigate the combined effect of mild stress and the lack of estrogen on mental disorders …

Play fighting during the juvenile period has been shown to be an important experience for
the development of sociocognitive skills and the underlying neural mechanisms that support …

Objective: Relapsing to overeating is a stubborn problem in obesity treatment. We tested the
hypothesis that context cues surrounding palatable food (PF) intake have the power to …

Environmental enrichment (EE) mimics positive life experiences by providing enhanced
social and physical stimulation. Placement into EE following weaning, or in later life, confers …