Obesity in aging exacerbates blood–brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes …
Z Tucsek, P Toth, D Sosnowska… - … Series A: Biomedical …, 2014 - academic.oup.com
There is growing evidence that obesity has deleterious effects on the brain and cognitive
function in the elderly population. However, the specific mechanisms through which aging …
function in the elderly population. However, the specific mechanisms through which aging …
Impact of immune-metabolic interactions on age-related thymic demise and T cell senescence
VD Dixit - Seminars in Immunology, 2012 - Elsevier
Emerging evidence indicates that the immune and metabolic interactions control several
aspects of the aging process and associated chronic diseases. Among several sites of …
aspects of the aging process and associated chronic diseases. Among several sites of …
Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox …
LC Bailey-Downs, Z Tucsek, P Toth… - … Series A: Biomedical …, 2013 - academic.oup.com
Obesity in the elderly individuals is increasing at alarming rates and there is evidence
suggesting that elderly individuals are more vulnerable to the deleterious cardiovascular …
suggesting that elderly individuals are more vulnerable to the deleterious cardiovascular …
Mortality benefit of recombinant human interleukin-1 receptor antagonist for sepsis varies by initial interleukin-1 receptor antagonist plasma concentration
NJ Meyer, JP Reilly, BJ Anderson… - Critical care …, 2018 - journals.lww.com
Objective: Plasma interleukin-1 beta may influence sepsis mortality, yet recombinant human
interleukin-1 receptor antagonist did not reduce mortality in randomized trials. We tested for …
interleukin-1 receptor antagonist did not reduce mortality in randomized trials. We tested for …
Markers of the progression of complications in patients with type 2 diabetes: a one-year longitudinal study
MC Preciado-Puga, JM Malacara… - Experimental and …, 2014 - thieme-connect.com
Hyperglycemia induces tissue damage and complications by mechanisms that produce
advanced glycation end-products (AGEs) and inflammation. To investigate the factors …
advanced glycation end-products (AGEs) and inflammation. To investigate the factors …
Plasma biomarkers of oxidative and AGE-mediated damage of proteins and glycosaminoglycans during healthy ageing: a possible association with ECM metabolism
K Komosinska-Vassev, P Olczyk… - Mechanisms of ageing …, 2012 - Elsevier
The aim of this study was to examine whether oxidative and AGE-mediated processes
correlates with the metabolic changes of proteoglycans (PGs) and proteins during …
correlates with the metabolic changes of proteoglycans (PGs) and proteins during …
Understanding the aging process using epidemiologic approaches
JL Sanders, RM Boudreau, AB Newman… - The epidemiology of …, 2012 - Springer
Recent research has identified that aging and disease are not synonymous and that aging
can be optimized. This has been demonstrated in animal models with genetic manipulation …
can be optimized. This has been demonstrated in animal models with genetic manipulation …
Correlation of endogenous secretory receptor for advanced glycation end product (esRAGE) with metabolic health related biomarkers of skeletal muscle
J Pajari - 2016 - jyx.jyu.fi
Pajari, J. 2016. Correlation of endogenous secretory receptor for advanced glycation end
product (esRAGE) with metabolic health associated biomarkers of skeletal muscle …
product (esRAGE) with metabolic health associated biomarkers of skeletal muscle …