Catalytic cross-coupling reactions have had a profound impact on the synthesis of
pharmaceuticals, biologically active natural products, and materials. 1 Such reactions …

This Perspective recapitulates recent developments of carbon dioxide utilization in carbon–
carbon bond formation reactions, with an intention of paving a way toward sustainable CO2 …

Transition Metal Reagents and Catalysts Innovations in Organic Synthesis Jiro Tsuji
Emeritus Professor, Tokyo Institute of Technology, Japan Numerous innovative and practical …

We have reported in 1965 that n-allylpalfadium chloride (1) reacts with C-nucleophiles such
as malonates, acetoacetates, and enamines (Eq. l), and shown that the reaction offers a new …

In 1965 we reported that (ir-allyl) palladium chloride reacts with carbonucleophiles such as
malonates, acetoacetates, and enamines, thereby offering a new method for carbon-carbon …

Palladium cross-coupling reactions: Heck, Sonogashira, Tsuji-Trost, Suzuki, Stille as well as
protecting group chemistry in aqueous media are presented. The excellent compatibility of …

The TV-tert-butyldimethylsilyloxycarbonyl group (silyl carbamate) was synthesized from
commonly used amino protecting groups such as TV-tert-butoxycarbonyl (Boc) and iV …

A number of ekctrophilic allylic derivatives which do not behave as allylating agents under
usual SN2 conditions, may do so, provided that catalytic amounts of appropriate soluble …

¿ V-Allyloxycarbonyl (Alloc) derivatives of amines and amino acids are quantitatively and
very rapidly converted to free amino compounds by palladium-catalyzed hydrostannolytic …

The structurally related macrolides FK506 and rapamycin have recently been shown to
inhibit distinct signaling pathways in T lymphocytes. 1'* 12 Whereas FK506 and the …