Keloid treatments: an evidence-based systematic review of recent advances

LA Walsh, E Wu, D Pontes, KR Kwan, S Poondru… - Systematic reviews, 2023 - Springer
Background Keloids are pathologic scars that pose a significant functional and cosmetic
burden. They are challenging to treat, despite the multitude of treatment modalities currently …

Updated international clinical recommendations on scar management: part 1—evaluating the evidence

MH Gold, B Berman, MT Clementoni… - Dermatologic …, 2014 - journals.lww.com
Updated International Clinical Recommendations on Scar Manag... : Dermatologic Surgery
Updated International Clinical Recommendations on Scar Management: Part 1—Evaluating …

Keloids and hypertrophic scars: a spectrum of clinical challenges

AP Trace, CW Enos, A Mantel, VM Harvey - American journal of clinical …, 2016 - Springer
Since their earliest description, keloids and hypertrophic scars have beleaguered patients
and clinicians alike. These scars can be aesthetically disfiguring, functionally debilitating …

Network meta-analysis of different clinical commonly used drugs for the treatment of hypertrophic scar and keloid

S Yang, YJ Luo, C Luo - Frontiers in Medicine, 2021 - frontiersin.org
Background: There is no uniform treatment for pathological scars, including keloids and
hypertrophic scars, in clinic currently. Previously, multiple randomized controlled trials have …

[PDF][PDF] Intralesional 5-fluorouracil in keloid treatment: a systematic review

E Bijlard, S Steltenpool, FB Niessen - Acta Derm Venereol, 2015 - nvpc.nl
Abstract In the 1990s, 5-fluorouracil (5-FU) was introduced as a treatment for keloids;
however, there is still no consensus on its use. In order to guide clinical practice, a …

New insights on keloids, hypertrophic scars, and striae

S Ud-Din, A Bayat - Dermatologic clinics, 2014 - derm.theclinics.com
Cutaneous dermal injury inevitably leads to scar formation. 1 The reparative process
involves inflammation, granulation tissue formation, and matrix remodeling, which can result …

Highly deformable and highly fluid vesicles as potential drug delivery systems: theoretical and practical considerations

EL Romero, MJ Morilla - International journal of Nanomedicine, 2013 - Taylor & Francis
Vesicles that are specifically designed to overcome the stratum corneum barrier in intact skin
provide an efficient transdermal (systemic or local) drug delivery system. They can be …

5-fluorouracil in the treatment of keloids and hypertrophic scars: a comprehensive review of the literature

VV Shah, AS Aldahan, S Mlacker, M Alsaidan… - Dermatology and …, 2016 - Springer
Hypertrophic (HTSs) and keloid scars are common dermatological complaints produced by
disruption of the normal wound-healing process. Despite a wide array of therapeutic options …

Strategic management of keloid disease in ethnic skin: a structured approach supported by the emerging literature

S Ud‐Din, A Bayat - British journal of dermatology, 2013 - academic.oup.com
Keloid disease (KD) is a common, benign, dermal fibroproliferative growth of unknown
aetiology. Lesions tend to grow over time; they often recur following therapy and do not …

Keloid excision and adjuvant treatments: a network meta-analysis

C Siotos, AC Uzosike, H Hong, SM Seal… - Annals of plastic …, 2019 - journals.lww.com
Background Keloid disease treatment continues to be unsatisfactory with high recurrence
rates. We evaluated the literature regarding the effectiveness of keloid excision with various …