The relative insufficiency of insulin secretion and/or insulin action causes diabetes.
However, obesity and type 2 diabetes mellitus can be associated with an absolute increase …

Diabetes mellitus is a metabolic disorder that affects more than 460 million people
worldwide. Type 1 diabetes (T1D) is caused by autoimmune destruction of β-cells, whereas …

Regenerative medicine, the most recent and emerging branch of medical science, deals
with functional restoration of tissues or organs for the patient suffering from severe injuries or …

Intrauterine adhesion refers to endometrial repair disorders which are usually caused by
uterine injury and may lead to a series of complications such as abnormal menstrual …

Cell encapsulation has been shown to hold promise for effective, long-term treatment of type
1 diabetes (T1D). However, challenges remain for its clinical applications. For example …

Chronically deregulated blood-glucose concentrations in diabetes mellitus result from a loss
of pancreatic insulin-producing β cells (type 1 diabetes, T1D) or from impaired insulin …

For the past century, insulin injections have saved millions of lives, but glycemic instability is
still a persistent challenge for people with diabetes, leading to tremendous morbidity and …

Incredible strides have been made since the discovery of insulin almost 100 years ago.
Insulin formulations have improved dramatically, glucose levels can be measured …

Recent years have seen an increased focus on human islet biology, and exciting findings in
the stem cell and genomic arenas highlight the need to define the key features of mature …

Development of stem cell technologies for cell replacement therapy has progressed rapidly
in recent years. Diabetes has long been seen as one of the first applications for stem cell …