Increased cancer burden among pesticide applicators and others due to pesticide exposure

MCR Alavanja, MK Ross… - CA: A Cancer Journal for …, 2013 - Wiley Online Library
A growing number of well‐designed epidemiological and molecular studies provide
substantial evidence that the pesticides used in agricultural, commercial, and home and …

Repair of O6-alkylguanine by alkyltransferases

AE Pegg - Mutation Research/Reviews in Mutation Research, 2000 - Elsevier
The predominant pathway for the repair of O6-methylguanine in DNA is via the activity of an
alkyltransferase protein that transfers the methyl group to a cysteine acceptor site on the …

Detailed review of transgenic rodent mutation assays

IB Lambert, TM Singer, SE Boucher… - … Research/Reviews in …, 2005 - Elsevier
Induced chromosomal and gene mutations play a role in carcinogenesis and may be
involved in the production of birth defects and other disease conditions. While it is widely …

Prostate cancer and ambient pesticide exposure in agriculturally intensive areas in California

M Cockburn, P Mills, X Zhang, J Zadnick… - American journal of …, 2011 - academic.oup.com
In a population-based case-control study in California's intensely agricultural Central Valley
(2005–2006), the authors investigated relations between environmental pesticide/fungicide …

Prostate cancer and toxicity from critical use exemptions of methyl bromide: environmental protection helps protect against human health risks

LT Budnik, S Kloth, M Velasco-Garrido, X Baur - Environmental Health, 2012 - Springer
Background Although ozone-depleting methyl bromide was destined for phase-out by 2005,
it is still widely applied as a consequence of various critical-use-exemptions and mandatory …

The toxic chemistry of methyl bromide

AT Bulathsinghala, IC Shaw - Human & experimental …, 2014 - journals.sagepub.com
Methyl bromide (MeBr) is a chemically reactive compound that has found use as a fire
retardant and fumigant used for wood, soil, fruits and grains. Its use is banned in many …

Effects of atrazine and chlorpyrifos on DNA methylation in the liver, kidney and gill of the common carp (Cyprinus carpio L.)

C Wang, Z Zhang, H Yao, F Zhao, L Wang… - Ecotoxicology and …, 2014 - Elsevier
Pesticide exposure has repeatedly been associated with cancers, although the molecular
mechanisms behind this association are largely undetermined. Abnormal DNA methylation …

Environmental exposure of humans to bromide in the Dead Sea area: Measurement of genotoxicy and apoptosis biomarkers

SD Nusair, MJ Almasaleekh, H Abder-Rahman… - … /Genetic Toxicology and …, 2019 - Elsevier
Bromide (Br−) is a bromine atom with a negative charge which is released mainly in the
production of pesticides and flame retardants. It is also found naturally in seawater. Br¯ has …

Mycofumigation through production of the volatile DNA-methylating agent N-methyl-N-nitrosoisobutyramide by fungi in the genus Muscodor

ML Hutchings, DA Hiller, J Berro, SA Strobel - Journal of Biological …, 2017 - ASBMB
Antagonistic microorganisms produce antimicrobials to inhibit the growth of competitors.
Although water-soluble antimicrobials are limited to proximal interactions via aqueous …

Pesticides and Cancer

T Roh, A Aggarwal, NT Hasan, A Upadhyay… - … Oncology: Theory and …, 2023 - Springer
Pesticides are widely used in agriculture to control weeds, insects, fungi, rodents, and other
pests, but their use can have negative effects on both the environment and human health …