Abstract ATPases Associated with Diverse Cellular Activity (AAA ATPase) are essential
enzymes found in all organisms. They are involved in various processes such as DNA …

Highlights•RUVBL1–RUVBL2 forms a scaffold in macromolecular complexes such as R2TP
and chromatin remodelers.•RUVBL1–RUVBL2 ATPase activity is regulated by client …

In this report, we developed a unified and standardized one-pot sequence that converts
pyridine derivatives into 1, 2-diazepines by inserting a nitrogen atom. This skeletal …

Abstract RNA polymerase II (Pol II) apparatuses are compartmentalized into transcriptional
clusters. Whether protein factors control these clusters remains unknown. In this study, we …

Abstract mRNA export is an essential pathway for the regulation of gene expression. In
humans, closely related RNA helicases, UAP56 and URH49, shape selective mRNA export …

In this paper, a highly efficient and regioselective synthesis of pyrazolone fused
benzodiazepine derivatives via the reaction of 1-phenylpyrazolidinones with propargyl …

Epigenetic dysregulation is reported in multiple cancers including Ewing sarcoma (EwS).
However, the epigenetic networks underlying the maintenance of oncogenic signaling and …

A catalytic system‐controlled divergent reaction strategy was here reported to construct four
types of intriguing spiroheterocyclic skeletons from simple and readily available starting …

Summary RUVBL1 and RUVBL2 (collectively RUVBL1/2) are essential AAA+ ATPases that
function as co-chaperones and have been implicated in cancer. Here we investigated the …

The PAQosome is an 11-subunit chaperone involved in the biogenesis of several human
protein complexes. We show that ASDURF, a recently discovered upstream open reading …