Ischemic stroke after cerebral artery occlusion is one of the major causes of chronic disability
worldwide. Interleukins (ILs) play a bidirectional role in ischemic stroke through information …

Cardiovascular diseases (CVDs) are the prevalent cause of mortality around the world.
Activation of inflammasome contributes to the pathological progression of cardiovascular …

Pyroptosis is a type of programmed cell death characterized by cell swelling and osmotic
lysis, resulting in cytomembrane rupture and release of immunostimulatory components …

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by multi-articular,
symmetrical and invasive arthritis resulting from immune system abnormalities involving T …

Abstract Background Neurodegenerative diseases (NDDs) are characterized by progressive
neuronal dysfunctionality which results in disability and human life-threatening events. In …

Background Parkinson's disease (PD) is a common neurodegenerative disease
characterized by motor symptoms and non-motor symptoms, and affects millions of people …

Cognitive impairment is a multifactorial and multi-step pathological process that places a
heavy burden on patients and the society. Neuroinflammation is one of the main factors …

Autophagy has been described to be both protective and pathogenic in cerebral
ischemia/reperfusion (I/R) injury. The underlying association between autophagy and …

The pathophysiology of vascular disease is linked to accelerated biological aging and a
combination of genetic, lifestyle, biological, and environmental risk factors. Within the …

Stroke is a threatening cerebrovascular disease caused by thrombus with high morbidity
and mortality rates. Neutrophils are the first to be recruited in the brain after stroke, which …