Taste receptor genes

AA Bachmanov, GK Beauchamp - Annu. Rev. Nutr., 2007 - annualreviews.org
In the past several years, tremendous progress has been achieved with the discovery and
characterization of vertebrate taste receptors from the T1R and T2R families, which are …

Genetics of taste and smell: poisons and pleasures

DR Reed, A Knaapila - Progress in molecular biology and translational …, 2010 - Elsevier
Eating is dangerous. While food contains nutrients and calories that animals need to
produce heat and energy, it may also contain harmful parasites, bacteria, or chemicals. To …

Opportunities for the replacement of animals in the study of nausea and vomiting

AM Holmes, JA Rudd, FD Tattersall… - British journal of …, 2009 - Wiley Online Library
Nausea and vomiting are among the most common symptoms encountered in medicine as
either symptoms of disease or side effects of treatments. Developing novel anti‐emetics and …

Psychophysical dissection of genotype effects on human bitter perception

JA Mennella, MY Pepino, FF Duke, DR Reed - Chemical senses, 2011 - academic.oup.com
The purpose of this study was to define the effects of individual polymorphisms within the
haplotypes of the TAS2R38 taste receptor gene on human bitter taste perception. A racially …

A biomimetic bitter receptor-based biosensor with high efficiency immobilization and purification using self-assembled aptamers

C Wu, L Du, L Zou, L Huang, P Wang - Analyst, 2013 - pubs.rsc.org
It is of substantial interest to mimic mechanisms of biological sensing systems for the
development of novel biosensors. This paper presents a novel biomimetic bitter receptor …

Behavioral genetics and taste

JD Boughter, AA Bachmanov - BMC neuroscience, 2007 - Springer
This review focuses on behavioral genetic studies of sweet, umami, bitter and salt taste
responses in mammals. Studies involving mouse inbred strain comparisons and genetic …

Label-free functional assays of chemical receptors using a bioengineered cell-based biosensor with localized extracellular acidification measurement

L Du, L Zou, L Zhao, L Huang, P Wang, C Wu - Biosensors and …, 2014 - Elsevier
New methods for functional assays of chemical receptors are highly essential for the
research of chemical signal transduction mechanisms and for the development of chemical …

Expression of mammalian GPCRs in C. elegansgenerates novel behavioural responses to human ligands

MS Teng, MPJ Dekkers, BL Ng, S Rademakers… - BMC biology, 2006 - Springer
Background G-protein-coupled receptors (GPCRs) play a crucial role in many biological
processes and represent a major class of drug targets. However, purification of GPCRs for …

[PDF][PDF] A REVIEW: A ROLE OF CAPSAICIN TO REGULATING T2R AND TRPV1 AND ITS ASSOCIATION IN CANCER DEVELOPMENT.

FR Ardi Putra, A Irmawati - Jurnal Biosains Pascasarjana, 2023 - e-journal.unair.ac.id
Cancer is one of the leading causes of death in the world. It is estimated that this disease
has caused 10 million deaths. The cause of the development of cells into cancer is still a …

Feline bitter taste receptors and methods

MM Sandau, NE Rawson - US Patent 9,169,311, 2015 - Google Patents
(57) ABSTRACT A family of novel feline bitter taste receptors, referred to as feline TAS2R
(fTAS2R), are disclosed herein. Isolated poly nucleotides encoding the novel feline bitter …