Novel electrode technologies for neural recordings

G Hong, CM Lieber - Nature Reviews Neuroscience, 2019 - nature.com
Neural recording electrode technologies have contributed considerably to neuroscience by
enabling the extracellular detection of low-frequency local field potential oscillations and …

Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications

Z Yan, B Rein - Molecular psychiatry, 2022 - nature.com
The prefrontal cortex (PFC) serves as the chief executive officer of the brain, controlling the
highest level cognitive and emotional processes. Its local circuits among glutamatergic …

[HTML][HTML] Longevity factor klotho enhances cognition in aged nonhuman primates

SA Castner, S Gupta, D Wang, AJ Moreno, C Park… - Nature aging, 2023 - nature.com
Cognitive dysfunction in aging is a major biomedical challenge. Whether treatment with
klotho, a longevity factor, could enhance cognition in human-relevant models such as in …

Review of the evidence on, and fundamental questions about, efforts to improve executive functions, including working memory

A Diamond, DS Ling - Cognitive and working memory training …, 2020 - books.google.com
Review of the evidence on, and fundamental questions about, efforts to improve executive
functions, including working memory Page 166 8 Review of the Evidence on, and Fundamental …

[HTML][HTML] The aging astrocyte transcriptome from multiple regions of the mouse brain

MM Boisvert, GA Erikson, MN Shokhirev, NJ Allen - Cell reports, 2018 - cell.com
Aging brains undergo cognitive decline, associated with decreased neuronal synapse
number and function and altered metabolism. Astrocytes regulate neuronal synapse …

The neuroscience of working memory capacity and training

C Constantinidis, T Klingberg - Nature Reviews Neuroscience, 2016 - nature.com
Working memory—the ability to maintain and manipulate information over a period of
seconds—is a core component of higher cognitive functions. The storage capacity of …

Persistent spiking activity underlies working memory

C Constantinidis, S Funahashi, D Lee… - Journal of …, 2018 - Soc Neuroscience
Persistent activity generated in the PFC during the delay period of working memory tasks
represents information about stimuli held in memory and determines working memory …

[HTML][HTML] Neuromodulation of prefrontal cortex cognitive function in primates: the powerful roles of monoamines and acetylcholine

R Cools, AFT Arnsten - Neuropsychopharmacology, 2022 - nature.com
The primate prefrontal cortex (PFC) subserves our highest order cognitive operations, and
yet is tremendously dependent on a precise neurochemical environment for proper …

Is adult ADHD a childhood-onset neurodevelopmental disorder? Evidence from a four-decade longitudinal cohort study

TE Moffitt, R Houts, P Asherson… - American Journal of …, 2015 - Am Psychiatric Assoc
Objective: Despite a prevailing assumption that adult ADHD is a childhood-onset
neurodevelopmental disorder, no prospective longitudinal study has described the …

[HTML][HTML] Neuronal timescales are functionally dynamic and shaped by cortical microarchitecture

R Gao, RL Van den Brink, T Pfeffer, B Voytek - Elife, 2020 - elifesciences.org
Complex cognitive functions such as working memory and decision-making require
information maintenance over seconds to years, from transient sensory stimuli to long-term …