Significance: The heme-enzyme myeloperoxidase (MPO) is one of the major neutrophil
bactericidal proteins and is stored in large amounts inside azurophilic granules of …

Atrial fibrosis with enhanced turnover and deposition of matrix proteins leads to
inhomogeneous atrial electrical conduction and gives rise to electrical reentry circuits …

Overproduction of hypochlorous acid (HOCl) has been associated with the development of a
variety of disorders such as inflammation, heart disease, pulmonary fibrosis, and cancer …

Here we show that hydroxyl radical (• OH) generated through the Fenton reaction alters
metaphase-II mouse oocyte microtubules (MT) and chromosomal alignment (CH) …

Hypochlorous acid (HOCl) is generated by myeloperoxidase, using chloride and hydrogen
peroxide as substrates. Here we demonstrate that HOCl alters metaphase‐II mouse oocyte …

Hypochlorous acid (HOC l) is a potent cytotoxic oxidant generated by the enzyme
myeloperoxidase (MPO) in the presence of hydrogen peroxide (H2O2) and chloride (Cl−) …

Objective: The study sought to identify whether a relationship exists between serum
myeloperoxidase (MPO) and free iron with stages of ovarian cancer. Methods: Serum and …

Objective To demonstrate the effects of peroxynitrite (ONOO−) on metaphase II mouse
oocyte spindle structure and chromosomal alignment in presence and absence of cumulus …

In inflammatory diseases, where hypochlorous acid (HOCl) is elevated, iron homeostasis is
disturbed, resulting in accumulation of free iron. Free iron is toxic by virtue of its ability to …

Ovarian cancer is the leading cause of death from gynecologic malignancies yet the
underlying pathophysiology is not clearly established. Epithelial ovarian cancer (EOC) has …