[HTML][HTML] The use of both therapeutic and prophylactic vaccines in the therapy of papillomavirus disease

AR Garbuglia, D Lapa, C Sias… - Frontiers in …, 2020 - frontiersin.org
Human papillomavirus (HPV) is the most common sexually transmitted virus. The high-risk
HPV types (ie, HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59) are considered to be the …

[HTML][HTML] HIV-1 and human genetic variation

PJ McLaren, J Fellay - Nature Reviews Genetics, 2021 - nature.com
Over the past four decades, research on the natural history of HIV infection has described
how HIV wreaks havoc on human immunity and causes AIDS. HIV host genomic research …

[HTML][HTML] Targeting CCR5 as a component of an HIV-1 therapeutic strategy

H Mohamed, T Gurrola, R Berman, M Collins… - Frontiers in …, 2022 - frontiersin.org
Globally, human immunodeficiency virus type 1 (HIV-1) infection is a major health burden for
which successful therapeutic options are still being investigated. Challenges facing current …

Preserved Central Memory and Activated Effector Memory CD4+ T-Cell Subsets in Human Immunodeficiency Virus Controllers: an ANRS EP36 Study

SJ Potter, C Lacabaratz, O Lambotte… - Journal of …, 2007 - Am Soc Microbiol
Human immunodeficiency virus (HIV) controllers are rare individuals who spontaneously
control HIV type 1 replication for 10 years or more in the absence of antiretroviral treatment …

CCR5 revisited: how mechanisms of HIV entry govern AIDS pathogenesis

A Brelot, LA Chakrabarti - Journal of Molecular Biology, 2018 - Elsevier
The chemokine receptor CCR5 has been the focus of intensive studies since its role as a
coreceptor for HIV entry was discovered in 1996. These studies lead to the development of …

[HTML][HTML] Host factors influencing susceptibility to HIV infection and AIDS progression

J Lama, V Planelles - Retrovirology, 2007 - Springer
Transmission of HIV first results in an acute infection, followed by an apparently
asymptomatic period that averages ten years. In the absence of antiretroviral treatment, most …

CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms

MJ Dolan, H Kulkarni, JF Camargo, W He, A Smith… - Nature …, 2007 - nature.com
Although host defense against human immunodeficiency virus 1 (HIV-1) relies mainly on cell-
mediated immunity (CMI), the determinants of CMI in humans are poorly understood. Here …

Genetics of resistance to HIV infection: Role of co-receptors and co-receptor ligands

F Arenzana-Seisdedos, M Parmentier - Seminars in immunology, 2006 - Elsevier
Susceptibility to HIV infection and AIDS progression is variable among individuals and
populations, and in part genetically determined. Genetic variants of genes encoding HIV co …

Case of yellow fever vaccine-associated viscerotropic disease with prolonged viremia, robust adaptive immune responses, and polymorphisms in CCR5 and RANTES …

B Pulendran, J Miller, TD Querec… - The Journal of …, 2008 - academic.oup.com
Background. The live attenuated yellow fever vaccine 17D (YF-17D) is one of the most
effective vaccines. Despite its excellent safety record, some cases of viscerotropic adverse …

Elite control of HIV infection: implications for vaccine design

BM Baker, BL Block, AC Rothchild… - Expert opinion on …, 2009 - Taylor & Francis
Background:'Elite controllers' are rare HIV-infected individuals who are able to
spontaneously control HIV replication without medication, maintaining viral loads that are …