The development and modelling of devices and paradigms for transcranial magnetic stimulation

SM Goetz, ZD Deng - International Review of Psychiatry, 2017 - Taylor & Francis
Magnetic stimulation is a non-invasive neurostimulation technique that can evoke action
potentials and modulate neural circuits through induced electric fields. Biophysical models …

Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals

J Liu, YS Kim, CE Richardson, A Tom, C Ramakrishnan… - Science, 2020 - science.org
The structural and functional complexity of multicellular biological systems, such as the
brain, are beyond the reach of human design or assembly capabilities. Cells in living …

In Situ Synthesis and Assembly of Functional Materials and Devices in Living Systems

W Wang, CD Sessler, X Wang, J Liu - Accounts of Chemical …, 2024 - ACS Publications
Conspectus Integrating functional materials and devices with living systems enables novel
methods for recording, manipulating, or augmenting organisms not accessible by traditional …

Perineuronal nets decrease membrane capacitance of peritumoral fast spiking interneurons in a model of epilepsy

BP Tewari, L Chaunsali, SL Campbell, DC Patel… - Nature …, 2018 - nature.com
Brain tumor patients commonly present with epileptic seizures. We show that tumor-
associated seizures are the consequence of impaired GABAergic inhibition due to an overall …

Janus microparticles-based targeted and spatially-controlled piezoelectric neural stimulation via low-intensity focused ultrasound

M Han, E Yildiz, U Bozuyuk, A Aydin, Y Yu… - Nature …, 2024 - nature.com
Electrical stimulation is a fundamental tool in studying neural circuits, treating neurological
diseases, and advancing regenerative medicine. Injectable, free-standing piezoelectric …

Optogenetic polymerization and assembly of electrically functional polymers for modulation of single-neuron excitability

CD Sessler, Y Zhou, W Wang, ND Hartley, Z Fu… - Science …, 2022 - science.org
Ionic conductivity and membrane capacitance are two foundational parameters that govern
neuron excitability. Conventional optogenetics has emerged as a powerful tool to …

Anatomical and technical factors affecting the neural response to epidural spinal cord stimulation

HJ Zander, RD Graham, CJ Anaya… - Journal of neural …, 2020 - iopscience.iop.org
Objective. Spinal cord stimulation (SCS) is a common neurostimulation therapy to treat
chronic pain. Computational models represent a valuable tool to study the potential …

Modeling the response of small myelinated axons in a compound nerve to kilohertz frequency signals

NA Pelot, CE Behrend, WM Grill - Journal of neural engineering, 2017 - iopscience.iop.org
Objective. There is growing interest in electrical neuromodulation of peripheral nerves,
particularly autonomic nerves, to treat various diseases. Electrical signals in the kilohertz …

Modeling ultrasound modulation of neural function in a single cell

HM Badawe, RH El Hassan, ML Khraiche - Heliyon, 2023 - cell.com
Background Low intensity ultrasound stimulation has been shown to non-invasively
modulate neural function in the central nervous system (CNS) and peripheral nervous …

Non-monotonic kilohertz frequency neural block thresholds arise from amplitude-and frequency-dependent charge imbalance

E Peña, NA Pelot, WM Grill - Scientific reports, 2021 - nature.com
Reversible block of nerve conduction using kilohertz frequency electrical signals has
substantial potential for treatment of disease. However, the ability to block nerve fibers …