Cyclic glycine-proline (cGP) normalises insulin-like growth factor-1 (IGF-1) function: Clinical significance in the ageing brain and in age-related neurological conditions

J Guan, F Li, D Kang, T Anderson, T Pitcher… - Molecules, 2023 - mdpi.com
Insulin-like growth factor-1 (IGF-1) function declines with age and is associated with brain
ageing and the progression of age-related neurological conditions. The reversible binding of …

Targeted capillary photothrombosis via multiphoton excitation of Rose Bengal

P Delafontaine-Martel, C Zhang, X Lu… - Journal of Cerebral …, 2023 - journals.sagepub.com
Microvascular stalling, the process occurring when a capillary temporarily loses perfusion,
has gained increasing interest in recent years through its demonstrated presence in various …

Cerebral tissue pO2 response to treadmill exercise in awake mice

M Moeini, C Cloutier-Tremblay, X Lu, A Kakkar… - Scientific Reports, 2020 - nature.com
We exploited two-photon microscopy and Doppler optical coherence tomography to
examine the cerebral blood flow and tissue pO2 response to forced treadmill exercise in …

Transient Changes in Cerebral Tissue Oxygen, Glucose, and Temperature by Microstrokes: A Computational Study

M Bagheri, S Habibzadeh, M Moeini - Microcirculation, 2024 - Wiley Online Library
Objective This study focuses on evaluating the disruptions in key physiological parameters
during microstroke events to assess their severity. Methods A mathematical model was …