Leptomeningeal carcinomatosis (LC) is a rare but challenging manifestation of advanced
breast cancer with a severe impact on morbidity and mortality. We performed a systematic …

Stereotactic radiosurgery (SRS) is a mainstay treatment option for brain metastasis (BM).
While guidelines for SRS use have been outlined by professional societies, consideration of …

Background Leptomeningeal disease (LMD) is a complication distinguished by progression
of metastatic disease into the leptomeninges and subsequent spread via cerebrospinal fluid …

HER2+ breast leptomeningeal carcinomatosis (HER2+ LC) occurs when tumor cells spread
to cerebrospinal fluid–containing leptomeninges surrounding the brain and spinal cord, a …

Purpose While leptomeningeal metastasis (LM) from estrogen receptor-positive, HER2-
negative advanced breast cancer (ER+ HER2-ABC) has a poor prognosis, the details of …

Purpose Hypofractionated stereotactic radiosurgery (HF-SRS) with or without surgical
resection is potentially a preferred treatment for larger or symptomatic brain metastases …

Introduction Neoadjuvant stereotactic radiosurgery (NaSRS) of brain metastases has gained
importance, but it is not routinely performed. While awaiting the results of prospective …

Non-small cell lung cancer (NSCLC) is currently the leading cause of cancer-related death
worldwide, and the incidence of brain metastases (BM) in NSCLC patients is continuously …

Simple Summary Leptomeningeal carcinomatosis (LC) is a rare event in breast cancer (BC)
patients that carries an abysmal prognosis. Little progress has been made in this field in the …

Background Despite reports on the efficacy of checkpoint inhibitor (CPI) immunotherapies
for metastatic cancers, there are limited data on the effectiveness of surgery for brain …