Unveiling the tumour-regulatory roles of miR-1275 in cancer

ZX Chong, SK Yeap, WY Ho, CM Fang - Pathology-Research and Practice, 2022 - Elsevier
The rapid development of small RNA and molecular biology research in the past 20 years
has enabled scientists to discover many new miRNAs that are proven to play essential roles …

Aberrant stem cell and developmental programs in pediatric leukemia

RE Ling, JW Cross, A Roy - Frontiers in Cell and Developmental …, 2024 - frontiersin.org
Hematopoiesis is a finely orchestrated process, whereby hematopoietic stem cells give rise
to all mature blood cells. Crucially, they maintain the ability to self-renew and/or differentiate …

MicroRNA profiling of paediatric AML with FLT-ITD or MLL-rearrangements: Expression signatures and in vitro modulation of miR-221-3p and miR-222-3p with …

PP Leoncini, P Vitullo, S Reddel… - Oncology …, 2022 - spandidos-publications.com
Novel therapeutic strategies are needed for paediatric patients affected by Acute Myeloid
Leukaemia (AML), particularly for those at high-risk for relapse. MicroRNAs (miRs) have …

[HTML][HTML] The inhibitory effect of sulforaphane on the proliferation of acute myeloid leukemia cell lines through controlling miR-181a

M Koolivand, M Ansari, S Moein, M Afsa… - Cell Journal …, 2022 - ncbi.nlm.nih.gov
Objective The present study investigated the role of miR-181a as a small non-coding RNA
molecule in acute myeloid leukemia (AML) pathogenesis and reflected on the effects of …

miR-144-3p Derived from Bone Marrow Mesenchymal Stem Cells (BMSCs) Restrains the Drug Resistance of Acute Myeloid Leukemia (AML)

J Wu, Y Xie, L Han - Journal of Biomaterials and Tissue …, 2022 - ingentaconnect.com
This study assessed whether miR-144-3p derived from BMSCs restrains the drug resistance
of AML. Our study intends to assess miR-144-3p's role in AML drug resistance. Drug …

[PDF][PDF] miR-4772-5p and miR-196b as potential prognostic biomarker in pediatric core binding factor acute myeloid leukemia

V Gaur, S Chaudhary, S Agarwal, SK Sharawat… - Health …, 2020 - researchgate.net
Introduction: Aberrant expression of miRNAs has been linked with the initiation and
progression of several cancers. However, their role as prognostic biomarkers in pediatric …