Development of assisted reproductive technologies has been driven by the goals of
reducing the incidence of infertility, increasing the number of offspring from genetically elite …

The preimplantation development of mammals generally follows the same plan. It starts with
the formation of a totipotent zygote, and through consecutive cleavage divisions and …

Oviductal extracellular vesicles (oEVs) are emerging as key players in the gamete/embryo–
oviduct interactions that contribute to successful pregnancy. Various positive effects of oEVs …

Embryo culture conditions are crucial as they can affect embryo quality and even offspring.
Oviductal extracellular vesicles (EVs) long been considered a major factor influencing …

Understanding the mechanisms underlying the first cell differentiation events in human
preimplantation development is fundamental for defining the optimal conditions for IVF …

The degradation of maternally provided molecules is a very important process during early
embryogenesis. However, the vast majority of studies deals with mRNA degradation and …

During the first days following fertilization, cells of mammalian embryo gradually lose
totipotency, acquiring distinct identity. The first three lineages specified in the mammalian …

The basic units of chromatin are nucleosomes, that are made up of DNA wrapped around
histone cores. Histone lysine residue is a common location for posttranslational …

The study's objectives were to examine the effects of electrofusion on rabbit somatic cell
nuclear transfer (SCNT) embryos, and to test melatonin as a protective agent against …

Background While mammalian embryos can adapt to their environments, their sensitivity
overshadows their adaptability in suboptimal in vitro conditions. Therefore, the environment …