Gangliosides are sialylated glycolipids, mainly present at the cell surface membrane,
involved in a variety of cellular signaling events. During malignant transformation, the …

Gangliosides are a large subfamily of glycosphingolipids that broadly exist in the nervous
system and interact with signaling molecules in the lipid rafts. GD3 and GD2 are two types of …

Survivin, a member of the inhibitor of apoptosis family of proteins (IAPs) that controls cell
division, apoptosis, metastasis and angiogenesis, is overexpressed in essentially all human …

Gangliosides are a class of important glycosphingolipids containing sialic acid that are
widely distributed on the outer surface of cells and are abundantly distributed in brain tissue …

Accumulating evidence suggests that micro RNAs (miRNAs) are over‐or under‐expressed
in tumors, and abnormalities in miRNA expression may contribute to carcinogenesis. MiR …

Growth arrest–specific gene 6 (GAS6) promotes growth and cell survival during tissue repair
and development in different organs, including the liver. However, the specific role of GAS6 …

Glycosphingolipids (GSLs) are a family of bioactive lipids that in addition to their role in the
regulation of structural properties of membrane bilayers have emerged as crucial players in …

Colorectal cancer (CRC) is one of the leading causes of cancer mortality worldwide.
Aberrant sialylation is crucially involved in the progression of various types of cancer …

The disialoganglioside GD3 is overexpressed in∼ 50% of invasive ductal breast carcinoma,
and the GD3 synthase gene (ST8SIA1) displays higher expression among estrogen receptor …

Hepatocellular carcinoma (HCC) frequently develops in a pro-inflammatory and pro-
fibrogenic environment with hepatic stellate cells (HSCs) remodeling the extracellular matrix …