The study of eukaryotic tRNA processing has given rise to an explosion of new information
and insights in the last several years. We now have unprecedented knowledge of each step …

Co-phase separation of RNAs and RNA-binding proteins drives the biogenesis of
ribonucleoprotein granules. RNAs can also undergo phase transitions in the absence of …

The seminal discovery of ribonuclease P (RNase P) and its catalytic RNA by Sidney Altman
has not only revolutionized our understanding of life, but also opened new fields for scientific …

Triple-negative breast cancer (TNBC) is currently the worst prognostic subtype of breast
cancer, and there is no effective treatment other than chemotherapy. Processing of …

A boron dipyrromethene (BODIPY)-based metal–organic framework (MOF) nanoemitter was
for the first time designed with enhanced electrochemiluminescence (ECL) intensity due to …

Background To date, breast cancer remains the primary cause of tumor-related death
among women, even though some leap-type developments of oncology have been done to …

The telomerase holoenzyme is critical for maintaining eukaryotic genome integrity. In
addition to a reverse transcriptase and an RNA template, telomerase contains additional …

Coordination of transcription and processing of RNA is a basic principle in regulation of
gene expression in eukaryotes. In the case of mRNA, coordination is primarily founded on a …

RNase MRP is an essential eukaryotic ribonucleoprotein complex involved in the maturation
of rRNA and the regulation of the cell cycle. RNase MRP is related to the ribozyme-based …

Ribonuclease P (RNase P) is an important ribonucleoprotein (RNP), responsible for the
maturation of the 5′ end of precursor tRNAs (pre-tRNAs). In all organisms, the cleavage …