Biomarkers in colorectal cancer: current research and future prospects

OO Ogunwobi, F Mahmood, A Akingboye - International journal of …, 2020 - mdpi.com
Colorectal cancer (CRC) is a leading cause of death worldwide, despite progress made in
detection and management through surgery, chemotherapy, radiotherapy, and …

DNA methylation biomarkers in colorectal cancer: Clinical applications for precision medicine

N Fatemi, S Tierling, HA Es, M Varkiani… - … journal of cancer, 2022 - Wiley Online Library
Colorectal cancer (CRC) is the second leading cause of cancer death worldwide that is
attributed to gradual long‐term accumulation of both genetic and epigenetic changes. To …

Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor …

E Van Cutsem, CH Köhne, I Láng… - Journal of Clinical …, 2011 - ascopubs.org
Purpose The addition of cetuximab to irinotecan, fluorouracil, and leucovorin (FOLFIRI) as
first-line treatment for metastatic colorectal cancer (mCRC) was shown to reduce the risk of …

Personalized medicine: recent progress in cancer therapy

A Hoeben, EAJ Joosten… - Cancers, 2021 - mdpi.com
Personalized medicine (PM) or precision medicine in oncology is an emerging approach for
tumor treatment and prevention that takes into account inter-and intra-tumor variability in …

The roadmap of colorectal cancer screening

E Ferlizza, R Solmi, M Sgarzi, L Ricciardiello… - Cancers, 2021 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the third most common form of cancer in terms
of incidence and the second in terms of mortality worldwide. CRC develops over several …

Prognostic biomarkers of cell proliferation in colorectal cancer (CRC): from immunohistochemistry to molecular biology techniques

A Kasprzak - Cancers, 2023 - mdpi.com
Simple Summary This review aims to shed light on the proliferative markers important in the
everyday clinical management of colorectal cancer (CRC), ranging from simple methods of …

Acoustic bioprinting of patient‐derived organoids for predicting cancer therapy responses

H Chen, Z Wu, Z Gong, Y Xia, J Li, L Du… - Advanced …, 2022 - Wiley Online Library
Cancer models, which are biologically representative of patient tumors, can predict the
treatment responses and help determine the most appropriate cancer treatment for …

Implications of intratumor heterogeneity on consensus molecular subtype (CMS) in colorectal cancer

S Chowdhury, M Hofree, K Lin, D Maru, S Kopetz… - Cancers, 2021 - mdpi.com
Simple Summary Colorectal cancer (CRC) has been divided into four consensus molecular
subtypes (CMS) using the unsupervised clustering of bulk transcriptomic data. The CMS …

Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis

B Kortüm, H Radhakrishnan, F Zincke, C Sachse… - Oncogene, 2022 - nature.com
Colorectal cancer (CRC) is the second-most common malignant disease worldwide, and
metastasis is the main culprit of CRC-related death. Metachronous metastases remain to be …

[HTML][HTML] Emerging roles for HMGA2 in colorectal cancer

X Wang, J Wang, J Wu - Translational Oncology, 2021 - Elsevier
Abstract HMGA2 (High Mobility Group AT-hook 2) has been reported to promote colorectal
cancer (CRC) development by regulating the transcription of target genes. It participates in …