Reviewing and updating the major molecular markers for stem cells

R Calloni, EAA Cordero, JAP Henriques… - Stem cells and …, 2013 - liebertpub.com
Stem cells (SC) are able to self-renew and to differentiate into many types of committed cells,
making SCs interesting for cellular therapy. However, the pool of SCs in vivo and in vitro …

[HTML][HTML] The role and specific mechanism of OCT4 in cancer stem cells: a review

Q Zhang, Z Han, Y Zhu, J Chen… - International journal of …, 2020 - synapse.koreamed.org
Recently, evidences show that cancer stem cells (CSCs) are a type of cancer cell group with
self-renewal and play a huge role in tumor recurrence, metastasis, and drug resistance …

Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis

JM Churko, P Garg, B Treutlein… - Nature …, 2018 - nature.com
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have become a
powerful tool for human disease modeling and therapeutic testing. However, their use …

Generating a non-integrating human induced pluripotent stem cell bank from urine-derived cells

Y Xue, X Cai, L Wang, B Liao, H Zhang, Y Shan… - PloS one, 2013 - journals.plos.org
Induced pluripotent stem cell (iPS cell) holds great potential for applications in regenerative
medicine, drug discovery, and disease modeling. We describe here a practical method to …

Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing

Y Wang, P Liang, F Lan, H Wu, L Lisowski, M Gu… - Journal of the American …, 2014 - jacc.org
Background: Human induced pluripotent stem cells (iPSCs) play an important role in
disease modeling and drug testing. However, the current methods are time-consuming and …

Hypoxia as a biomarker for radioresistant cancer stem cells

C Peitzsch, R Perrin, RP Hill… - International journal of …, 2014 - Taylor & Francis
Background: Tumor initiation, growth and relapse after therapy are thought to be driven by a
population of cells with stem cell characteristics, named cancer stem cells (CSC). The …

MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells

CJC Parr, S Katayama, K Miki, Y Kuang, Y Yoshida… - Scientific reports, 2016 - nature.com
The efficiency of pluripotent stem cell differentiation is highly variable, often resulting in
heterogeneous populations that contain undifferentiated cells. Here we developed a …

Microfluidic single-cell analysis of transplanted human induced pluripotent stem cell–derived cardiomyocytes after acute myocardial infarction

SG Ong, BC Huber, W Hee Lee, K Kodo, AD Ebert… - Circulation, 2015 - Am Heart Assoc
Background—Human induced pluripotent stem cells (iPSCs) are attractive candidates for
therapeutic use, with the potential to replace deficient cells and to improve functional …

Signature of circular RNAs in human induced pluripotent stem cells and derived cardiomyocytes

W Lei, T Feng, X Fang, Y Yu, J Yang, ZA Zhao… - Stem cell research & …, 2018 - Springer
Abstract Background Circular RNAs (circRNAs) are regarded as a novel class of noncoding
RNA regulators. Although a number of circRNAs have been identified by bioinformatics …

COUP-TFII in health and disease

S Polvani, S Pepe, S Milani, A Galli - Cells, 2019 - mdpi.com
The nuclear receptors (NRs) belong to a vast family of evolutionary conserved proteins
acting as ligand-activated transcription factors. Functionally, NRs are essential in …