It is conceivable that spermatid apico-basal polarity and spermatid planar cell polarity (PCP)
are utmost important to support spermatogenesis. The orderly arrangement of developing …

Disease recurrence and metastasis lead to poor prognosis in patients with advanced
endometrial carcinoma (EC). RNA-binding proteins (RBPs) are closely associated with …

Background: Long non-coding RNA bladder cancer associated transcript 1 (BLACAT1) is
oncogenic in several types of cancers. However, little is known concerning its expression …

Thienopyrimidines containing a thiophene ring fused to pyrimidine are reported to have a
wide-spectrum of anticancer efficacy in vitro. Here, we report for the first time that thieno [3, 2 …

Wnt signaling is involved in embryo development and cancer. The binding between the DIX
domains of Axin1/2, Dishevelled1/2/3, and Coiled-coil-DIX1 is essential for Wnt/β-catenin …

Purpose Early biochemical recurrence (eBCR) indicated a high risk for potential recurrence
and metastasis in prostate cancer. The N6-methyladenosine (m6A) methylation modification …

Dishevelled (DVL) is the central signal transducer in both Wnt/β-catenin-dependent and
independent signalling pathways. DVL is required to connect receptor complexes and …

Background The qualitative transcriptional characteristics, the within‐sample relative
expression orderings (REOs) of genes, are highly robust against batch effects and sample …

Background: Previously reported transcriptional signatures for predicting the recurrence risk
of prostate cancer (PCa) patients after radical prostatectomy are mainly based on risk …

Thienopyrimidines are a versatile group of compounds that contain a biologically active
pharmacophore and reported to have anticancer efficacy in vitro. Here, we report for the first …