The statistical mechanics of dynamic pathways to self-assembly
S Whitelam, RL Jack - Annual review of physical chemistry, 2015 - annualreviews.org
This review describes some important physical characteristics of the pathways (ie,
dynamical processes) by which molecular, nanoscale, and micrometer-scale self-assembly …
dynamical processes) by which molecular, nanoscale, and micrometer-scale self-assembly …
How crystals form: A theory of nucleation pathways
JF Lutsko - Science advances, 2019 - science.org
Recent advances in classical density functional theory are combined with stochastic process
theory and rare event techniques to formulate a theoretical description of nucleation …
theory and rare event techniques to formulate a theoretical description of nucleation …
Molecular nucleation mechanisms and control strategies for crystal polymorph selection
AES Van Driessche, N Van Gerven, PHH Bomans… - Nature, 2018 - nature.com
The formation of condensed (compacted) protein phases is associated with a wide range of
human disorders, such as eye cataracts, amyotrophic lateral sclerosis, sickle cell anaemia …
human disorders, such as eye cataracts, amyotrophic lateral sclerosis, sickle cell anaemia …
Nucleation of metastable aragonite CaCO3 in seawater
Predicting the conditions in which a compound adopts a metastable structure when it
crystallizes out of solution is an unsolved and fundamental problem in materials synthesis …
crystallizes out of solution is an unsolved and fundamental problem in materials synthesis …
Nonclassical nucleation pathways in protein crystallization
F Zhang - Journal of Physics: Condensed Matter, 2017 - iopscience.iop.org
Classical nucleation theory (CNT), which was established about 90 years ago, has been
very successful in many research fields, and continues to be the most commonly used theory …
very successful in many research fields, and continues to be the most commonly used theory …
Ritonavir Form III: A new polymorph after 24 years
Polymorphism occurs widely in pharmaceutical solids, and must be thoroughly studied
during product development. Twenty-four years after ritonavir (RTV) Form II materialized, we …
during product development. Twenty-four years after ritonavir (RTV) Form II materialized, we …
Observing classical nucleation theory at work by monitoring phase transitions with molecular precision
It is widely accepted that many phase transitions do not follow nucleation pathways as
envisaged by the classical nucleation theory. Many substances can traverse intermediate …
envisaged by the classical nucleation theory. Many substances can traverse intermediate …
Ostwald Rule of Stages─ Myth or Reality?
PT Cardew - Crystal Growth & Design, 2023 - ACS Publications
In 1897, following a number of crystallization studies, Ostwald suggested that if a system has
a number of metastable states open to it then it proceeds sequentially by means of the …
a number of metastable states open to it then it proceeds sequentially by means of the …
Classical nucleation theory approach to two-step nucleation of crystals
D Kashchiev - Journal of Crystal Growth, 2020 - Elsevier
Crystals may not always nucleate directly in the supersaturated old phase, but rather in a
precursory metastable phase. This so-called two-step (2S) nucleation of crystals has …
precursory metastable phase. This so-called two-step (2S) nucleation of crystals has …
A dynamical theory of nucleation for colloids and macromolecules
JF Lutsko - The Journal of chemical physics, 2012 - pubs.aip.org
A general theory of nucleation for colloids and macromolecules in solution is formulated
within the context of fluctuating hydrodynamics. A formalism for the determination of …
within the context of fluctuating hydrodynamics. A formalism for the determination of …