[HTML][HTML] Optimizing autologous stem cell mobilization strategies to improve patient outcomes: consensus guidelines and recommendations

S Giralt, L Costa, J Schriber, J DiPersio… - Biology of Blood and …, 2014 - Elsevier
Autologous hematopoietic stem cell transplantation (aHSCT) is a well-established treatment
for malignancies such as multiple myeloma (MM) and lymphomas. Various changes in the …

The biology and clinical uses of blood stem cells

LB To, DN Haylock, PJ Simmons… - Blood, The Journal of …, 1997 - ashpublications.org
''It seems more than ever likely that blood-derived stem tive capacity. 47-49 In the allogeneic
setting, mobilized blood cells have also been used instead of BM. 50 Umbilical cord cells …

Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration

D Lucas, C Scheiermann, A Chow, Y Kunisaki… - Nature medicine, 2013 - nature.com
Anticancer chemotherapy drugs challenge hematopoietic tissues to regenerate but
commonly produce long-term sequelae. Chemotherapy-induced deficits in hematopoietic …

Factors that influence collection and engraftment of autologous peripheral-blood stem cells.

W Bensinger, F Appelbaum, S Rowley… - Journal of Clinical …, 1995 - ascopubs.org
PURPOSE To analyze factors that affect the collection of peripheral-blood stem cells (PBSC)
before transplant and the tempo of engraftment after transplant. PATIENTS AND METHODS …

[HTML][HTML] Impact of mobilization and remobilization strategies on achieving sufficient stem cell yields for autologous transplantation

I Pusic, SY Jiang, S Landua, GL Uy, MP Rettig… - Biology of Blood and …, 2008 - Elsevier
The purpose of this article was to examine historic institutional autologous stem cell
mobilization practices and evaluate factors influencing mobilization failure and kinetics. In …

Categorizing a prognostic variable: review of methods, code for easy implementation and applications to decision‐making about cancer treatments

M Mazumdar, JR Glassman - Statistics in medicine, 2000 - Wiley Online Library
Categorizing prognostic variables is essential for their use in clinical decision‐making. Often
a single cutpoint that stratifies patients into high‐risk and low‐risk categories is sought …

[HTML][HTML] Poor mobilization of hematopoietic stem cells—definitions, incidence, risk factors, and impact on outcome of autologous transplantation

P Wuchter, D Ran, T Bruckner, T Schmitt… - Biology of Blood and …, 2010 - Elsevier
As more efficient agents for stem cell mobilization are being developed, there is an urgent
need to define which patient population might benefit from these novel drugs. For a precise …

Peripheral blood stem cell transplants for multiple myeloma: identification of favorable variables for rapid engraftment in 225 patients

G Tricot, S Jagannath, D Vesole, J Nelson, S Tindle… - 1995 - ashpublications.org
Transfusion of autologous peripheral blood stem cells (PBSCs) of good quality ensures fast
hematopoietic engraftment after myeloablative therapy with a decrease in procedure-related …

[PDF][PDF] Therapeutic relevance of CD34 cell dose in blood cell transplantation for cancer therapy

S Siena, R Schiavo, P Pedrazzoli… - Journal of Clinical …, 2000 - Citeseer
Purpose: To review recent advances in peripheralblood progenitor-cell (PBPC)
transplantation in order to define the optimal cell dose required for autologous and …

Proposed definition of 'poor mobilizer'in lymphoma and multiple myeloma: an analytic hierarchy process by ad hoc working group Gruppo ItalianoTrapianto di Midollo …

A Olivieri, M Marchetti, R Lemoli, C Tarella… - Bone marrow …, 2012 - nature.com
Many lymphoma and myeloma patients fail to undergo ASCT owing to poor mobilization.
Identification of poor mobilizers (PMs) would provide a tool for early intervention with new …