Testicular torsion is a urological emergency that involves the twisting of the spermatic cord
along its course. Compelling pieces of evidence have implicated oxidative stress-sensitive …

This review compiles information from the literature on the chemical composition,
pharmacological effects, and molecular mechanisms of earthworm extract (EE) and …

Objective The objective of this study was to evaluate the role of oxidative stress in an
experimental model of streptozotocin-induced diabetic nephropathy in rats. Materials and …

Ethnopharmacological relevance Abelmoschus manihot (L.) medic (AM) is a natural
medicinal plant used for the treatment of chronic kidney disease (CKD) in China. Huangkui …

Diabetic nephropathy (DN) is characterized by inflammatory responses and extracellular
matrix (ECM) accumulation. Astilbin is an active natural compound and possesses anti …

Background Currently, no drug is available to directly target the signaling molecules
involved in the pathogenesis of diabetic nephropathy (DN); only antihypertensive and …

Introduction: The renin–angiotensin system and epithelial–mesenchymal transition play
crucial roles in the development of kidney fibrosis. The connection between the renin …

Context: Total flavones extracted from Abelmoschus manihot L.(Malvaceae) medic (TFA)
have been proven clinically effective at improving renal inflammation and glomerular injury …

Background The potential benefits of earthworm (Pheretima aspergillum) for healing have
received considerable attention recently. Osteoblast and osteoclast activities are very …

Background Diabetes mellitus (DM) is a major risk factor for contrast-induced acute kidney
injury (CI-AKI). DM and CI-AKI result in oxidative damage and inflammation that can be …