Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Fluorogenic probes, small-molecule sensors that unmask brilliant fluorescence upon
exposure to specific stimuli, are powerful tools for chemical biology. Those probes that …

A supramolecular fluorescent probe based on double-cavity nor-seco-cucurbit [10] uril (ns-Q
[10]) was constructed using the non-covalent host-guest interactions between ns-Q [10] and …

A near-infrared (NIR) fluorescent probe (SWJT-1) based on Cdouble bondN isomerization
was designed and synthesized for the detection of ClO–. SWJT-1 showed an excellent NIR …

Protein S-acylation is a prevalent post-translational protein lipidation that is dynamically
regulated by 'writer'protein S-acyltransferases and 'eraser'acylprotein thioesterases. The …

Here, we describe the development of a MOF-derived hierarchically porous ZrO2-supported
iridium catalyst (Ir-N@ HP-mesoZrO2), featuring sufficient accessible catalytic sites even …

The reversible modification of cysteine residues by thioester formation with palmitate (S-
palmitoylation) is an abundant lipid post-translational modification (PTM) in mammalian …

Formate is a major reactive carbon species in one-carbon metabolism, where it serves as an
endogenous precursor for amino acid and nucleic acid biosynthesis and a cellular source of …

Enzymes are macromolecular biological catalysts which can accelerate chemical reactions
in living organisms. Almost all the physiological metabolism activities in the cell need …

The superoxide anion (O2•–) and hydroxyl radical (• OH) are important reactive oxygen
species (ROS) used as biomarkers in physiological and pathological processes. ROS …