Oral squamous cell carcinomas: state of the field and emerging directions

Y Tan, Z Wang, M Xu, B Li, Z Huang, S Qin… - International journal of …, 2023 - nature.com
Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …

Role of exosomal non-coding RNAs from tumor cells and tumor-associated macrophages in the tumor microenvironment

Z Xu, Y Chen, L Ma, Y Chen, J Liu, Y Guo, T Yu… - Molecular Therapy, 2022 - cell.com
Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …

Extracellular vesicles in ovarian cancer chemoresistance, metastasis, and immune evasion

W Tian, N Lei, J Zhou, M Chen, R Guo, B Qin, Y Li… - Cell Death & …, 2022 - nature.com
Chemoresistance and metastasis are the major challenges for the current ovarian cancer
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …

Expression, regulation, and function of exosome‐derived miRNAs in cancer progression and therapy

B Li, Y Cao, M Sun, H Feng - The FASEB Journal, 2021 - Wiley Online Library
Exosomes are a novel class of intercellular signal modulators that contain a wide range of
molecules and deliver information between cells and tissues. MicroRNAs (miRNAs), a type …

The role of miRNAs in ovarian cancer pathogenesis and therapeutic resistance–a focus on signaling pathways interplay

A Ismail, AI Abulsoud, D Fathi, A Elshafei… - … -Research and Practice, 2022 - Elsevier
One of the most prevalent and lethal forms of gynecological cancer is ovarian cancer (OC),
which is often diagnosed in its latter, deadly stages. The OC's high mortality and …

Exosomes promote pre-metastatic niche formation in ovarian cancer

W Feng, DC Dean, FJ Hornicek, H Shi, Z Duan - Molecular cancer, 2019 - Springer
Ovarian cancer is one of the most common gynecological malignancies. Upon initial
diagnosis, the majority of patients present with widespread metastatic growth within the …

Non-coding RNAs regulation of macrophage polarization in cancer

S Mohapatra, C Pioppini, B Ozpolat, GA Calin - Molecular cancer, 2021 - Springer
Noncoding RNA (ncRNA) transcripts that did not code proteins but regulate their functions
were extensively studied for the last two decades and the plethora of discoveries have …

Role of non-coding RNAs and RNA modifiers in cancer therapy resistance

X Zhang, K Xie, H Zhou, Y Wu, C Li, Y Liu, Z Liu, Q Xu… - Molecular cancer, 2020 - Springer
As the standard treatments for cancer, chemotherapy and radiotherapy have been widely
applied to clinical practice worldwide. However, the resistance to cancer therapies is a major …

RETRACTED ARTICLE: exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer

M Han, J Hu, P Lu, H Cao, C Yu, X Li, X Qian… - Cell death & …, 2020 - nature.com
Trastuzumab is commonly used in the treatment of human epidermal growth factor receptor-
2 positive (HER-2+) breast cancer, but its efficacy is often limited by the emergence of …

The role of extracellular vesicles in the hallmarks of cancer and drug resistance

CPR Xavier, HR Caires, MAG Barbosa, R Bergantim… - Cells, 2020 - mdpi.com
Extracellular vesicles (EVs) mediate intercellular signaling and communication, allowing the
intercellular exchange of proteins, lipids, and genetic material. Their recognized role in the …