Physical and digital phantoms for 2D and 3D x-ray breast imaging: Review on the state-of-the-art and future prospects

A Sarno, C Valero, RM Tucciariello, N Dukov… - Radiation Physics and …, 2023 - Elsevier
Breast phantoms are a fundamental asset both in routine quality assurance programs and
for comparing scanner performance in 2D and 3D x-ray breast imaging. They also play an …

Performance evaluation of digital breast tomosynthesis systems: comparison of current virtual clinical trial methods

NW Marshall, H Bosmans - Physics in Medicine & Biology, 2022 - iopscience.iop.org
Virtual clinical trials (VCT) have been developed by a number of groups to study breast
imaging applications, with the focus on digital breast tomosynthesis imaging. In this review …

Patient‐derived heterogeneous breast phantoms for advanced dosimetry in mammography and tomosynthesis

M Caballo, C Rabin, C Fedon… - Medical …, 2022 - Wiley Online Library
Background Understanding the magnitude and variability of the radiation dose absorbed by
the breast fibroglandular tissue during mammography and digital breast tomosynthesis …

Knowledge-based in silico models and dataset for the comparative evaluation of mammography AI for a range of breast characteristics, lesion conspicuities and doses

E Sizikova, N Saharkhiz, D Sharma… - Advances in …, 2024 - proceedings.neurips.cc
To generate evidence regarding the safety and efficacy of artificial intelligence (AI) enabled
medical devices, AI models need to be evaluated on a diverse population of patient cases …

The stochastic digital human is now enrolling for in silico imaging trials—methods and tools for generating digital cohorts

A Badano, MA Lago, E Sizikova… - Progress in …, 2023 - iopscience.iop.org
Randomized clinical trials, while often viewed as the highest evidentiary bar by which to
judge the quality of a medical intervention, are far from perfect. In silico imaging trials are …

Virtual clinical trials in 2D and 3D x-ray breast imaging and dosimetry: Comparison of CPU-based and GPU-based Monte Carlo codes

G Mettivier, A Sarno, Y Lai, B Golosio, V Fanti… - Cancers, 2022 - mdpi.com
Simple Summary Virtual clinical trials in X-ray breast imaging may permit substantial
reduction of the costs, times, and exposure risk to patient of clinical trials. Monte Carlo …

Thermoplastic 3D printing technology using a single filament for producing realistic patient-derived breast models

N Dukov, K Bliznakova, N Okkalidis… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective. This work describes an approach for producing physical anthropomorphic breast
phantoms from clinical patient data using three-dimensional (3D) fused-deposition …

Fabrication of 3D printed patient-derived anthropomorphic breast phantoms for mammography and digital breast tomosynthesis: Imaging assessment with clinical X …

A Varallo, A Sarno, R Castriconi, A Mazzilli, A Loria… - Physica Medica, 2022 - Elsevier
Purpose To design, fabricate and characterize 3D printed, anatomically realistic,
compressed breast phantoms for digital mammography (DM) and digital breast …

Attenuation coefficient in the energy range 14–36 keV of 3D printing materials for physical breast phantoms

G Mettivier, A Sarno, A Varallo… - Physics in Medicine & …, 2022 - iopscience.iop.org
Objective. To measure the monoenergetic x-ray linear attenuation coefficient, μ, of fused
deposition modeling (FDM) colored 3D printing materials (ABS, PLA white, PLA orange, PET …

Comparisons of glandular breast dose between digital mammography, tomosynthesis and breast CT based on anthropomorphic patient-derived breast phantoms

A Sarno, G Mettivier, K Bliznakova, AM Hernandez… - Physica Medica, 2022 - Elsevier
Purpose To evaluate the bias to the mean glandular dose (MGD) estimates introduced by
the homogeneous breast models in digital breast tomosynthesis (DBT) and to have an …