Cardiovascular diseases (CVD) are the number one cause of morbidity and death
worldwide. As estimated by the WHO, the global death rate from CVD is 31% wherein, a …

The coagulation system has gained much interest again as new anticoagulatory substances
have been introduced into clinical practice. Especially patients with renal failure are likely …

The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the …

BACKGROUND: A minority of patients having cardiac procedures (15% to 20%) consume
more than 80% of the blood products transfused at operation. Blood must be viewed as a …

Patients with end‐stage renal disease (ESRD) develop hemostatic disorders mainly in the
form of bleeding diatheses. Hemorrhage can occur at cutaneous, mucosal, or serosal sites …

Discussion DR. JOSEPH W. ESCHBACH (Clinical Professor of Nephrol-ogy, University of
Washington School of Medicine, Seattle, Washington): The association of anemia with renal …

Seminars in Thrombosis and Hemostasis (STH) celebrates 50 years of publishing in 2024.
To celebrate this landmark event, STH is republishing some archival material. This …

Most biomedical textbooks teach that coagulation and thrombosis are primarily a function of
endothelial cells, platelets, and soluble coagulation factors. Red blood cells, in contrast, are …

The main indication for the transfusion of plasma is to correct deficiencies of clotting factors,
for which a specific concentrate is not available, in patients with active bleeding. The …

Platelet-adhesive mechanisms play a well-defined role in hemostasis and thrombosis, but
evidence continues to emerge for a relevant contribution to other pathophysiological …