Hyaluronic acid (also known as hyaluronan or hyaluronate) is naturally found in many
tissues and fluids, but more abundantly in articular cartilage and synovial fluid (SF) …

Although the predominant mechanism of intra-articular hyaluronan (hyaluronic acid)(HA)
and hylans for the treatment of pain associated with knee osteoarthritis (OA) is unknown, in …

Background: Hyaluronan, or hyaluronic acid (HA), is the major hydrodynamic nonprotein
component of joint synovial fluid (SF). Its unique viscoelastic properties confer remarkable …

Current techniques in biological resurfacing of cartilage defects require an open arthrotomy
or arthroscopy and involve the direct transplantation of isolated cells and/or scaffolds or …

目的综述透明质酸钠在关节内的生理功能以及在关节疾病中的临床应用. 方法广泛查阅相关文献
资料, 分析透明质酸钠治疗关节疾病的机制及应用前景. 结果外源性透明质酸钠通过参与改善 …

PURPOSE: Conservative, nonsurgical therapies for basal joint osteoarthritis, such as thumb
spica splinting and intra-articular corticosteroid injections, remain the mainstays for …

Adult human mesenchymal stem cells (hMSC) are involved in wound healing and
regeneration of mesodermal tissue, but the underlying homing mechanisms are not well …

Hyaluronic acid (HA) has been widely used for viscosupplementation of diseased or aged
articular joints. However, recent investigations have revealed the active anti-inflammatory or …

Rheumatoid arthritis (RA) is a systemic and chronic autoimmune inflammatory disorder
affecting multiple joints. Various cytokines, chemokines and growth factors synergistically …

Background: In recent years, the involvement of the soluble urokinase Plasminogen
Activator Receptor (suPAR) in the pathophysiological modulation of Rheumatoid Arthritis …