Stem cell-based therapies for spinal cord injury

RS Nandoe Tewarie, A Hurtado… - The journal of spinal …, 2009 - Taylor & Francis
Spinal cord injury (SCI) results in loss of nervous tissue and consequently loss of motor and
sensory function. There is no treatment available that restores the injury-induced loss of …

Balancing ethical pros and cons of stem cell derived gametes

S Segers, H Mertes, G de Wert, W Dondorp… - Annals of biomedical …, 2017 - Springer
In this review we aim to provide an overview of the most important ethical pros and cons of
stem cell derived gametes (SCD-gametes), as a contribution to the debate about …

[图书][B] The family: A liberal defence

D Archard - 2010 - books.google.com
Page 1 Dalgſave macmillan The Family: A Liberal Defence David Archard Page 2 The Family:
A Liberal Defence Page 3 Also by David Archard MARXISM AND EXISTENTIALISM: The …

Multiplex parenting: IVG and the generations to come

C Palacios-González, J Harris, G Testa - Journal of medical ethics, 2014 - jme.bmj.com
Recent breakthroughs in stem cell differentiation and reprogramming suggest that functional
human gametes could soon be created in vitro. While the ethical debate on the uses of in …

In vitro eugenics

R Sparrow - Journal of Medical Ethics, 2014 - jme.bmj.com
A series of recent scientific results suggest that, in the not-too-distant future, it will be
possible to create viable human gametes from human stem cells. This paper discusses the …

Drawing the line on in vitro gametogenesis

L Notini, C Gyngell, J Savulescu - Bioethics, 2020 - Wiley Online Library
In vitro gametogenesis (IVG) might offer numerous research and clinical benefits. Some
potential clinical applications of IVG, such as allowing opposite‐sex couples experiencing …

[HTML][HTML] Procreative beneficence and in vitro gametogenesis

H Bourne, T Douglas, J Savulescu - Monash Bioethics Review, 2012 - ncbi.nlm.nih.gov
The Principle of Procreative Beneficence (PB) holds that when a couple plans to have a
child, they have significant moral reason to select, of the possible children they could have …

In vitro differentiation of germ cells from stem cells: a comparison between primordial germ cells and in vitro derived primordial germ cell-like cells

W Ge, C Chen, M De Felici, W Shen - Cell death & disease, 2015 - nature.com
Stem cells are unique cell types capable to proliferate, some of them indefinitely, while
maintaining the ability to differentiate into a few or any cell lineages. In 2003, a group …

Potential consequences of clinical application of artificial gametes: a systematic review of stakeholder views

S Hendriks, W Dondorp, G de Wert… - Human …, 2015 - academic.oup.com
BACKGROUND Recent progress in the formation of artificial gametes, ie gametes generated
from progenitors or somatic cells, has led to scientific and societal discussion about their use …

Differentiation of mesenchymal stem cells to germ‐like cells under induction of Sertoli cell‐conditioned medium and retinoic acid

R Ghaem Maghami, T Mirzapour, A Bayrami - Andrologia, 2018 - Wiley Online Library
The aim of this research was to find a way to differentiate germ cells from umbilical cord
Wharton's jelly mesenchymal stem cells (MSCs) to support in vitro spermatogenesis. A small …