This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

This paper introduces a new construct, the 'pivotal mental state', which is defined as a hyper-
plastic state aiding rapid and deep learning that can mediate psychological transformation …

Psychedelics have attracted medical interest, but their effects on human brain function are
incompletely understood. In a comprehensive, within-subjects, placebo-controlled design …

The recent devastating pandemic has drastically reminded humanity of the importance of
constant scientific and technological progress. A strong interdisciplinary dialogue between …

Recent clinical trials show that psychedelics such as LSD and psilocybin can be given safely
in controlled conditions, and can cause lasting psychological benefits with one or two …

Abstract N, N-dimethyltryptamine (DMT) is distinct among classic serotonergic psychedelics
because of its short-lasting effects when administered intravenously. Despite growing …

Studying transitions in and out of the altered state of consciousness caused by intravenous
(IV) N, N-Dimethyltryptamine (DMT-a fast-acting tryptamine psychedelic) offers a safe and …

How profoundly can humans change their own minds? In this paper we offer a unifying
account of deconstructive meditation under the predictive processing view. We start from …

Can the use of psychedelic drugs induce lasting changes in metaphysical beliefs? While it is
popularly believed that they can, this question has never been formally tested. Here we …

Some people seem to have a 'talent'for spiritual experience: they readily sense the presence
of supernatural beings, receive special messages from God, and report intense feelings of …