Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases

E Beurel, SF Grieco, RS Jope - Pharmacology & therapeutics, 2015 - Elsevier
Abstract Glycogen synthase kinase-3 (GSK3) may be the busiest kinase in most cells, with
over 100 known substrates to deal with. How does GSK3 maintain control to selectively …

[HTML][HTML] Traumatic brain injury and Alzheimer's disease: the cerebrovascular link

J Ramos-Cejudo, T Wisniewski, C Marmar… - …, 2018 - thelancet.com
Traumatic brain injury (TBI) and Alzheimer's disease (AD) are devastating neurological
disorders, whose complex relationship is not completely understood. Cerebrovascular …

[HTML][HTML] In vivo base editing of post-mitotic sensory cells

WH Yeh, H Chiang, HA Rees, ASB Edge… - Nature …, 2018 - nature.com
Programmable nucleases can introduce precise changes to genomic DNA through
homology-directed repair (HDR). Unfortunately, HDR is largely restricted to mitotic cells, and …

Low‐level laser therapy for traumatic brain injury in mice increases brain derived neurotrophic factor (BDNF) and synaptogenesis

W Xuan, T Agrawal, L Huang, GK Gupta… - Journal of …, 2015 - Wiley Online Library
Transcranial low‐level laser (light) therapy (LLLT) is a new non‐invasive approach to
treating a range of brain disorders including traumatic brain injury (TBI). We (and others) …

[HTML][HTML] Chemotherapy-induced cognitive impairment and hippocampal neurogenesis: a review of physiological mechanisms and interventions

MJ Sekeres, M Bradley-Garcia… - International journal of …, 2021 - mdpi.com
A wide range of cognitive deficits, including memory loss associated with hippocampal
dysfunction, have been widely reported in cancer survivors who received chemotherapy …

Peripheral blood brain-derived neurotrophic factor in bipolar disorder: a comprehensive systematic review and meta-analysis

K Munkholm, M Vinberg, LV Kessing - Molecular psychiatry, 2016 - nature.com
Peripheral blood brain-derived neurotrophic factor (BDNF) has been proposed as a
potential biomarker related to disease activity and neuroprogression in bipolar disorder …

[HTML][HTML] What's new in traumatic brain injury: update on tracking, monitoring and treatment

C Reis, Y Wang, O Akyol, WM Ho… - International journal of …, 2015 - mdpi.com
Traumatic brain injury (TBI), defined as an alteration in brain functions caused by an external
force, is responsible for high morbidity and mortality around the world. It is important to …

Neuroprotective kynurenine metabolite indices are abnormally reduced and positively associated with hippocampal and amygdalar volume in bipolar disorder

J Savitz, R Dantzer, BE Wurfel, TA Victor… - …, 2015 - Elsevier
Inflammation-related changes in the concentrations of kynurenine-pathway metabolites
occur in depression secondary to medical conditions but have not been well characterized …

Extracellular nucleotides and P2 receptors in renal function

V Vallon, R Unwin, EW Inscho… - Physiological …, 2020 - journals.physiology.org
The understanding of the nucleotide/P2 receptor system in the regulation of renal
hemodynamics and transport function has grown exponentially over the last 20 yr. This …

Role of Wnt signaling in central nervous system injury

C Lambert, P Cisternas, NC Inestrosa - Molecular Neurobiology, 2016 - Springer
The central nervous system (CNS) is highly sensitive to external mechanical damage,
presenting a limited capacity for regeneration explained in part by its inability to restore …